Visian^® ICLV4c™ and Artiflex^®: Comparative Analysis with the HD Analyser^TM and Integration with Subjective Performance and Anatomical Parameters

Figures & data

Table 1 Baseline Characteristics per PIOL

	Visian^® ICLV4c™	Artiflex^®	P
	N=30	N=30
Demographic data (mean ± standard deviation)
Age (years)	35.3 ± 5.9	37.6 ± 5.2	0.262
Gender, M/F	6/9	7/8	1.000*
Follow-up (months)	38.5 ± 10.1	40.7 ±10.7	0.430
Clinical data (mean ± standard deviation)
CDVA (decimal) [LogMAR]	0.86 ±0.11 [0.066]	0.89 ± 0.15 [0.051]	0.190
SE (diopters)	(-)8.25 ± 2.6	(-)8.64 ± 2.6	0.566
Sphere (diopters)	(-)7.38 ± 2.7	(-)7.62 ± 2.4	0.719
Cylinder (diopters)	(-)1.76 ± 1.3	(-)2.05 ± 1.6	0.438
Anatomical parameters (mean ± standard deviation)
ACD (mm)	3.19 ± 0.15	3.26 ± 0.16	0.096
ACV (mm^3)	186.67 ± 27.3	206.45 ± 22.7	<0.001
ACA (°)	39.1 ± 4.4	41.5 ± 7.4	0.122
ECD (cells/mm^2)	2978.5 ± 408	2976.3 ± 266	0.980
Pupillary diameter (mm)	3.26 ± 0.61	3.56 ± 0.73	0.094

Notes: Statistical significance at p<0.05 (bold), *Fisher’s exact test.

Abbreviations: M, male; F, female; CDVA, corrected distance visual acuity; SE, spherical equivalent; ACD, anterior chamber depth; ACV, anterior chamber volume; ACA, anterior chamber angle; ECD, central endothelial cell density.

Figure 1 Visual acuities at baseline and at the end of follow-up (all eyes).

Figure 2 Visual acuity differences between baseline and the end of follow-up (all eyes).

Figure 3 Subjective spherical equivalent at the end of follow-up (all eyes).

Table 2 End of Follow-Up Visual Acuity and Quality of Vision per PIOL

	Visian^® ICLV4c™	Artiflex^®	P
	N=30	N=30
Visual acuity and refractive results
UDVA (decimal) [LogMAR]	0.95 ± 0.11 [0.022]	0.99 ± 0.05 [0.004]	0.027
UDVA ≥ 1.0 (decimal)	18/30	28/30	0.005*
≥ 1 Snellen line gain	12/30	11/30	1.000*
Plano target (≤0.5D SE)	28/30	27/30	1.000*
SE (diopters)	(-)0.53	(-)0.65
DEQ (diopters)	0.78	0.90
Efficacy Index	1.105	1.112
HD Analyser^TM results
OSI	1.79 ± 0.9	2.14 ± 1.6	0.306
MTF cutoff frequency	26.91 ± 9.2	26.51 ± 11.9	0.784
PVA (decimal)	0.887 ± 0.31	0.880 ± 0.39	0.942
PVA20 (decimal)	0.640 ± 0.24	0.627 ± 0.27	0.841
PVA9 (decimal)	0.387 ± 0.14	0.377 ± 0.16	0.800
Questionnaire results – scores
Satisfaction Score	55.7 ± 3.5	54.3 ± 5.4	0.386
Dysphotopsia Score	3.1 ± 1.8	2.1 ± 2.2	0.213
Questionnaire results – patient reports (n=30)
Glare sensitivity	9/15	6/15	0.196*
Day halos	1/15	2/15	0.671*
Night halos	5/15	4/15	0.779*

Notes: Statistical significance at p<0.05 (bold), *Fisher’s exact test.

Abbreviations: UDVA, uncorrected distance visual acuity; SE, spherical equivalent; DEQ, defocus equivalent; OSI, objective scatter index; MTF, modulation transfer function; PVA, predicted visual acuity within 100% contrast level; PVA20, predicted visual acuity within 20% contrast level; PVA9, predicted visual acuity within 9% contrast level.

Table 3 End of Follow-Up Anatomical Parameters and Its Variation from Baseline per PIOL

	Visian^® ICLV4c™	Artiflex^®	P
	N=30	N=30
Anatomical parameters (mean ± standard deviation)
ACD (mm)	3.08 ± 0.15**	3.07 ± 0.16**	0.812
ACV (mm^3)	147.40 ± 17.6	177.77 ± 12.3	<0.001
ACA (°)	26.4 ± 4.9	41.1 ± 6.2	<0.001
ECD (cells/mm^2)	2778.9 ± 309	2741.2 ± 477	0.537
Pupillary diameter (mm)	3.09 ± 0.57	2.75 ± 0.36	0.007
Variation (mean ± standard deviation)
ACD (mm)	(-)0.11 ± 0.08	(-)0.18 ± 0.13	0.008
ACV (mm^3)	(-)39.26 ± 25.5	(-)30.30 ± 23.2	0.213
ACA (°)	(-)12.66 ± 4.7	(-)0.48 ± 6.2	<0.001
ECD (%)	(-)6.7 ± 8	(-)7.9 ± 9	0.615
Pupillary diameter (mm)	(-)0.17 ± 0.7	(-)0.81 ± 0.7	<0.001

Notes: **Distance between corneal endothelium and PIOL, statistical significance at p<0.05 (bold).

Abbreviations: ACD, anterior chamber depth; ACV, anterior chamber volume; ACA, anterior chamber angle; ECD, central endothelial cell density; IOP, intraocular pressure.

Table 4 Subgroup Analysis, End of Follow-Up

	Toric	Non-Toric	P	Glare	No Glare	P	Scotopic Halos	No Scotopic Halos	P
	Eyes=44	Eyes=16		Patients=15	Patients=15		Patients=9	Patients=21
UCVA (decimal)	0.96 ± 0.09	0.99 ± 0.05	0.168	0.98 ± 0.08	0.96 ± 0.09	0.227	0.99 ± 0.10	0.96 ± 0.08	0.324
OSI	2.07 ± 1.3	1.66 ± 1.3	0.209	1.60 ± 1.1	2.33 ± 1.4	0.029	1.67 ± 1.2	2.13 ± 1.3	0.237
MTF	25.82 ± 10.8	29.15 ± 9.91	0.284	30.13 ± 9.8	23.29 ± 10.3	0.011	28.29 ± 9.4	26.03 ± 11.1	0.423
PVA (decimal)	0.86 ± 0.37	0.96 ± 0.30	0.157	1.01 ± 0.34	0.76 ± 0.32	0.005	0.94 ± 0.34	0.86 ± 0.36	0.418
PVA20 (decimal)	0.62 ± 0.26	0.68 ± 0.23	0.189	0.71 ± 0.25	0.55 ± 0.24	0.013	0.67 ± 0.22	0.62 ± 0.27	0.480
PVA9 (decimal)	0.37 ± 0.16	0.41 ± 0.13	0.194	0.43 ± 0.15	0.34 ± 0.15	0.020	0.41 ± 0.13	0.37 ± 0.16	0.392
Baseline SE (D)	8.55 ± 2.6	8.16 ± 2.8	0.628	8.98 ± 2.5	7.92 ± 2.7	0.115	9.29 ± 2.8	8.09 ± 2.4	0.128
Pupillary diameter (mm)	2.88 ± 0.48	3.01 ± 0.56	0.383	3.12 ± 0.54	2.71 ± 0.37	0.001	3.05 ± 0.55	2.71 ± 0.33	0.510

Note: Statistical significance at p<0.05 (bold).

Abbreviations: UCVA, uncorrected visual acuity; OSI, objective scatter index; MTF, modulation transfer function; PVA, predicted visual acuity within 100% contrast level; PVA20, predicted visual acuity within 20% contrast level; PVA9, predicted visual acuity within 9% contrast level; SE, spherical equivalent.