Surgical Outcomes of Primary Congenital Glaucoma in Children Under One Year from the Nile Delta

Figures & data

Table 1 Patients’ Demographics and Clinical Characteristics

Item	No (%)
Age at surgery (months)
Mean	5.2±2.9
Range	1–11
Median	5
Gender:
Male	12 (46.1%)
Female	14 (53.8%)
Laterality:
Unilateral	8 (30.7%)
Bilateral	18 (69.2%)
Presenting signs
Lacrimation	14/26 (53.8%)
Corneal signs:	24/26 (92.3%)
Haze	20/26 (76.9%)
Scar	4/26 (15.3%)
Buphthalmos	9/26 (34.6%)
IOP lowering medications:
Preoperative	11/26 (42.3%)
Postoperative	10/26 (38.4%)
Follow up (months)
Mean	18.5±11.8
Range	6–48
Median	16

Table 2 Main Disease Parameters Before and After Surgery and Degree of Improvement

Parameter	Preoperative Mean ±SD (Range)	Postoperative* Mean ±SD (Range)	Improvement
IOP, mmHg	28.5±4 (17 to 37)	12.4±4.1 (0 to 24)	16.1 (56.4%)
HCD, mm	13.7±0.7 (12 to 15.5)	12.9±0.9 (10.5 to 15.5)	0.8 (5.8%)
CDR	0.65±0.18 (0.2 to 0.9)	0.3±0.2 (0.7 to 0)	0.35 (53.8%)

Note: *Data recorded at the last postoperative visit.

Abbreviations: IOP, intraocular pressure; HCD, horizontal corneal diameter; CDR, cup-to- disc ratio.

Figure 1 Scatter plot comparing preoperative IOP with IOP at final follow-up visit.

Notes: Dots below the diagonal orange line represent subjects with lower IOP at final follow-up compared to their preoperative baseline IOP. The horizontal dotted line marks the 22mmHg success point, so that all points below this line are considered as success.

Table 3 Binary Logistic Regression Analysis for Predictors of Success

Variable	β	OR	95% CI	P-value
Age	0.375	1.46	1.01–2.11	0.022*
Preoperative IOP	−0.189	1.28	1.01–1.45	0.032*

Notes: β, regression coefficient (negative sign means negative effect). *Significant P-value (less than 0.05).

Abbreviations: OR, odds ratio; CI, confidence interval.

Figure 2 Kaplan–Meier survival analysis curve for the whole study eyes.

Figure 3 Clinical photos of a case complicated with sever persistent hypotony secondary to cyclitic membrane.

Notes: (A) UBM shows very shallow anterior chamber, peripheral anterior synechia, cyclitic membrane and ciliary body detachment. (B) B-scan ultrasound shows thickening of choroid and annular cilio-choroidal detachment. (C) Intraoperative appearance during debulking of the cyclitic membrane after removal of the crystalline lens.