Figures & data
Table 1 Demographic Data and Possible Predisposing Factors
Figure 1 Diagrams of infiltration pattern and clinical slit-lamp photographs. (A1 and A2) Diagram of a reticular infiltration pattern and a photograph of a 21-year-old student who had a history of contact-lens wearing and presented at KCMH two days after left eye irritation (Case#21); (B1 and B2) diagram of a satellite infiltration pattern and a photograph of a 55-year-old farmer who had a trauma to the right eye from grass leaves (Case#15); (C1 and C2) diagram of a multifocal infiltration pattern and a photograph of a 58-year-old farmer who had a trauma of the right eye with soil contamination (Case#24); (D1 and D2) diagram of a total infiltration pattern and a photograph of the right eye of a 61-year-old female without a significant history of ocular trauma (Case#10).
![Figure 1 Diagrams of infiltration pattern and clinical slit-lamp photographs. (A1 and A2) Diagram of a reticular infiltration pattern and a photograph of a 21-year-old student who had a history of contact-lens wearing and presented at KCMH two days after left eye irritation (Case#21); (B1 and B2) diagram of a satellite infiltration pattern and a photograph of a 55-year-old farmer who had a trauma to the right eye from grass leaves (Case#15); (C1 and C2) diagram of a multifocal infiltration pattern and a photograph of a 58-year-old farmer who had a trauma of the right eye with soil contamination (Case#24); (D1 and D2) diagram of a total infiltration pattern and a photograph of the right eye of a 61-year-old female without a significant history of ocular trauma (Case#10).](/cms/asset/c6f46210-1f0f-48a6-987d-8777db918cef/doph_a_12177297_f0001_c.jpg)
Table 2 Clinical and Diagnostic Data
Table 3 Demographic Data and histopathology of Globe Salvage Group versus Globe Removal Group (Categorical Variables)
Table 4 Demographic Data and Histopathology of Globe Salvage Group versus Globe Removal Group (Continuous Variables)
Figure 2 Box plot demonstrates that almost all of the cases from the globe salvage group received their first medical treatment on day 1 after onset of symptoms (asterisks indicate extreme outliers).
![Figure 2 Box plot demonstrates that almost all of the cases from the globe salvage group received their first medical treatment on day 1 after onset of symptoms (asterisks indicate extreme outliers).](/cms/asset/cd17138e-1a67-4e1f-9765-068a0a3d4814/doph_a_12177297_f0002_b.jpg)
Figure 3 Histopathology of Pythium keratitis in a globe salvage case (Case#19). (A) Histopathology section shows an ulcerated corneal lesion with numerous acute inflammatory cells and necrotic cells primarily located at the anterior stroma (Hematoxylin-Eosin); (B) special stain shows varying sizes of short hyphae at the posterior stroma and pre-Descemet’s membrane area (Gomori Methenamine Silver).
![Figure 3 Histopathology of Pythium keratitis in a globe salvage case (Case#19). (A) Histopathology section shows an ulcerated corneal lesion with numerous acute inflammatory cells and necrotic cells primarily located at the anterior stroma (Hematoxylin-Eosin); (B) special stain shows varying sizes of short hyphae at the posterior stroma and pre-Descemet’s membrane area (Gomori Methenamine Silver).](/cms/asset/7c011d0e-ec28-4401-afa9-402eef230bef/doph_a_12177297_f0003_c.jpg)
Figure 4 Histopathology of Pythium keratitis in globe salvage case (Case#05). (A) Histopathology section shows numerous acute inflammatory cells and necrotic cells in the corneal stroma (Hematoxylin-Eosin); (B) special stain shows varying-sized short hyphae at the mid stroma (Gomori Methenamine Silver).
![Figure 4 Histopathology of Pythium keratitis in globe salvage case (Case#05). (A) Histopathology section shows numerous acute inflammatory cells and necrotic cells in the corneal stroma (Hematoxylin-Eosin); (B) special stain shows varying-sized short hyphae at the mid stroma (Gomori Methenamine Silver).](/cms/asset/0faf120a-06ca-4d2f-9b67-0df28afb7e40/doph_a_12177297_f0004_c.jpg)
Figure 5 Histopathology of Pythium keratitis in globe removal case (Case#23). (A) Histopathology section shows numerous acute inflammatory cells and necrotic cells in the corneal stroma (Hematoxylin-Eosin); (B) special stain shows numerous varying-sized short hyphae with rare septation (Gomori Methenamine Silver).
![Figure 5 Histopathology of Pythium keratitis in globe removal case (Case#23). (A) Histopathology section shows numerous acute inflammatory cells and necrotic cells in the corneal stroma (Hematoxylin-Eosin); (B) special stain shows numerous varying-sized short hyphae with rare septation (Gomori Methenamine Silver).](/cms/asset/1a395376-fa11-4efe-a9b5-a3800e3343c5/doph_a_12177297_f0005_c.jpg)