Revisiting the Robustness of Pentacam HR Indices Against Soft Contact Lens Wear

Figures & data

Table 1 Demographic Data, Corrected Distance Visual Acuity (CDVA), and Refractive Spherical Equivalent for the 2 Studied Groups

	Group 1	Group 2	Mann–Whitney U-Test
	Median (IQR)	Median (IQR)	P value
Age, years	26.00(6.0)	26.00(4.0)	0.199
CDVA^a, logMAR	0.00(0.0)	0.00(0.0)	1.00
SE^b, diopter	−2.00(2.5)	−3.25(0.91)	0.065
			CHI square
			P value
Gender, m:f N,%	36:54, 40%:60%	44:46, 49%:51%	0.294

Note: P values are considered significant if ≤0.05.

Abbreviations: ^aCDVA, corrected distance visual acuity; ^bSE, spherical equivalent.

Table 2 Medians, Interquartile Ranges (IQR), Minimum (Min) and Maximum (Max) Values of the Various Pentacam HR Indices for the 2 Studied Groups, and P values of Significance Between the 2 Groups

	Group 1	Group 2	Mann–Whitney U-Test
	Median (IQR)	Median (IQR)	P value
K mean^a (min-max)	44.10(1.82)	43.25(1.22)	<0.001
	(41.50–46.80)	(40.80–45.50)
K max ^b (min-max)	45.30(2.00)	44.45(1.40)	<0.001
	(42.80–48.20)	(41.30–47.50)
ISV ^c (min-max)	19.0(9.0)	16.0(12.0)	<0.001
	(12–38)	(9–37)
IHD^d (min-max)	0.0120(0.010)	0.0090(0.004)	<0.001
	(0.002–0.030)	(0.03–0.140)
AE from BFS^e (min-max)	3.0(2.0)	3.0(2.0)	0.004
	(−1–7)	(−1–5)
PE from BFS^f (min-max)	6.0(4.0)	6.0(3.0)	0.533
	(1–13)	(0–10)
AE from BFTE^g (min-max)	0.0(1.0)	0.0(1.0)	0.155
	(−1–3)	(−2–3)
PE from BFTE^h (min-max)	2.0(2.0)	1.0(2.0)	0.064
	(−2–5)	(−2–3)
CCT^i (min-max)	545.5(53.0)	533.5(40.0)	0.447
	(486.0–628.0)	(482.0–598.0)
TCT^j (min-max)	541.0(55.0)	528.5(42.0)	0.383
	(480.0–620.0)	(485.0–596.0)
PPI avg^k (min-max)	1.060(0.18)	0.950(0.11)	<0.001
	(0.85–1.30)	(0.73–1.13)
PPI max^l (min-max)	1.350(0.20)	1.200(0.17)	<0.001
	(0.98–1.62)	(0.96–1.60)
ART max^m (min-max)	393.5(77.0)	444.0(75.0)	<0.001
	(310.0–559.0)	(322.0–608.0)

Notes: P values are considered significant if ≤0.05. Significant P values are in bold.

Abbreviations: ^aK mean, mean keratometry; ^bK max, maximum keratometry; ^cISV, index of surface variance; ^dIHD, index of height decentration; ^eAE from BFS, anterior elevation from the best-fit sphere; ^fPE from BFS, posterior elevation from the best-fit sphere; ^gAE from BFTE, anterior elevation from the best fit toric ellipsoid; ^hPE from BFTE, posterior elevation from the best-fit toric ellipsoid; ⁱCCT, thickness at pupil centroid; ^jTCT, the thinnest-point thickness; ^kPPI avg, average corneal pachymetry progression index; ^lPPI max, maximum corneal pachymetry progression index; ^mART max, maximum Ambrosio’s relational thickness index; min, minimum; max, maximum.

Figure 1 Boxplot of some curvature Pentacam-HR indices values in group 1 corneas before and 1month after the Soft Contact Lens (SCL) discontinuation period. (A) K max: Maximum keratometry, (B) K mean: Mean keratometry, (C) ISV: index of surface variance.

Figure 2 Boxplot of some elevation and pachymetric Pentacam-HR indices values in group 1 corneas before and 1month after the Soft Contact Lens (SCL) discontinuation period. (A) AE from BFS: anterior elevation from the best-fit sphere, (B) PE from BFS: posterior elevation from the best-fit sphere, (C) PPI avg: average corneal pachymetry progression index, (D) PPI max: maximum corneal pachymetry progression index.

Table 3 Medians, Interquartile Ranges (IQR), and Comparisons of Various Pentacam HR Indices in Group 1 Before and After Soft Contact Lens (SCL) Discontinuation

	SCL Wearers	SCL Wearers After Discontinuation for 1 Month	Wilcoxon Signed-Rank Test
	Median (IQR)	Median (IQR)	P value
K mean^a	44.10(1.82)	43.60(1.90)	<0.001
K max ^b	45.30(2.00)	44.75(1.83)	<0.001
ISV ^c	19.0(9.0)	13.0(10.0)	<0.001
IHD^d	0.0120(0.010)	0.0110(0.008)	<0.001
AE from BFS^e	3.0(2.0)	1.0(2.0)	0.850
PE from BFS^f	6.0(4.0)	1.0(3.0)	0.889
AE from BFTE^g	0.0(1.0)	3.0(4.0)	0.917
PE from BFTE^h	2.0(2.0)	6.0(4.0)	0.886
CCT^i	545.5(53.0)	545.0(53.0)	0.459
TCT^j	541.0(55.0)	542.0(54.0)	0.644
PPI avg^k	1.060(0.18)	0.930(0.20)	<0.001
PPI max^l	1.350(0.20)	1.210(0.21)	<0.001
ART max^m	393.5(77.0)	454.5(107.0)	<0.001

Notes: P values are considered significant if ≤0.05. Significant P values are in bold.

Abbreviations: ^aK mean, mean keratometry; ^bK max, maximum keratometry; ^cISV, index of surface variance; ^dIHD, index of height decentration; ^eAE from BFS, anterior elevation from the best-fit sphere; ^fPE from BFS, posterior elevation from the best-fit sphere; ^gAE from BFTE, anterior elevation from the best fit toric ellipsoid; ^hPE from BFTE, posterior elevation from the best-fit toric ellipsoid; ⁱCCT, thickness at pupil centroid; ^jTCT, the thinnest-point thickness; ^kPPI avg, average corneal pachymetry progression index; ^lPPI max, maximum corneal pachymetry progression index; ^mART max, maximum Ambrosio’s relational thickness index.