Utility of IOLMaster 700 Swept-Source Optical Coherence Tomography in Detecting Macular Disease for Preoperative Cataract Surgery Patients

Figures & data

Table 1 Preoperative Patient Demographics and Ocular Characteristics

Number of Patients	578 (1156 Eyes)
Gender
Male	226 (39.1%)
Female	352 (60.9%)
Preoperative visual acuity
20/20–20/25	12.3%
20/30–20/40	29.8%
20/50–20/60	24.1%
20/70–20/80	11.1%
20/100–20/250	12.3%
20/300–20/600	4.7%
Count fingers or worse	5.6%
Abnormal fundoscopy findings
Drusen (including extramacular)	47 (4.1%)
Poor view	25 (2.2%)
Retinal pigment epithelium mottling/irregularity	23 (2.0%)
Epiretinal membrane	19 (1.6%)
Microaneurysms or retinal hemorrhages	12 (1.0%)
Vascular attenuation	11 (1.0%)
Macular hole	6 (0.5%)
Other	37 (3.2%)

Figure 1 Representative swept-source OCT of normal foveas. (A–C) Representative IOLMaster 700 SS-OCT of three different non-pathological foveas, with inner retinal (IR) layers, outer retina (OR) layers, Bruch’s Membrane (BM), retinal pigment epithelium (RPE), photoreceptor layer (PR), and choroid (CH) layer denoted.

Table 2 Analysis of Efficacy of SS-OCT and SD-OCT in Detecting Macular Pathology and Most Common Macular Pathologies Identified

Total eyes with both SS-OCT and SD-OCT = 327
“Normal” SS-OCT = 206 eyes
Normal SD-OCT = 84 eyes		True negative = 40.8%
Abnormal SD-OCT = 122 eyes		False negative = 59.2%
“Abnormal” SS-OCT = 121 eyes
Normal SD-OCT = 17 eyes		False positive = 14.0%
Abnormal SD-OCT = 104 eyes		True positive = 86.0%
	Among eyes with abnormal SS-OCT and SD-OCT (true positive, 104 eyes)	Among eyes with normal SS-OCT and abnormal SD-OCT (false negative, 122 eyes)	Among all abnormal SD-OCT (226 eyes)
Epiretinal membrane	38 (36.5%)	33 (27.0%)	71 (31.4%)
Drusen	27 (26.0%)	19 (15.5%)	46 (20.4%)
Macular hole	10 (9.6%)	6 (4.9%)	16 (7.1%)
Cystoid macular edema	7 (6.7%)	8 (6.6%)	15 (6.6%)
Diabetic macular edema	4 (3.8%)	7 (5.3%)	11 (4.9%)
Other (including non-central macular edema, retinal dystrophy, degenerative myopia, macular scars)	31 (29.8%)	49 (41.0%)	80 (35.4%)

Figure 2 Epiretinal membrane appearance on swept-source OCT and spectral-domain OCT. (A–C, left) IOLMaster 700 SS-OCT scans of three different eyes with epiretinal membranes, demonstrating foveal thickening and intraretinal cystic spaces (arrowheads). (A–C, right) Corresponding Spectralis SD-OCT scans of epiretinal membranes (arrows) for comparison.

Figure 3 Macular edema appearance on swept-source OCT and spectral-domain OCT. (A and B, left) IOLMaster 700 SS-OCT scans of two different eyes with macular edema, demonstrating retinal thickening with intraretinal (black arrowheads) and subretinal fluid (black arrow). (A and B, right) Corresponding Spectralis SD-OCT scans of macular edema with intraretinal (white arrowheads) and subretinal (white arrow) fluid.

Figure 4 Drusen appearance on swept-source and spectral-domain OCT. (A–C, left) IOLMaster 700 SS-OCT scans of three different eyes with macular drusen (arrowheads) and retinal pigment epithelium (RPE) layer deformation (arrows). (A–C, right) Corresponding Spectralis SD-OCT scans of drusen (arrowheads) with RPE deformation (arrows).

Figure 5 Macular hole appearance on swept-source and spectral-domain OCT. (A and B, left) IOLMaster 700 SS-OCT scans of two different eyes with macular holes. (A and B, right) Corresponding Spectralis SD-OCT scans of macular holes.