Incidence and Risk Factors for Retinopathy of Prematurity (ROP) in Biggest Neonatal Intensive Care Unit in Itay Elbaroud City, Behera Province, Egypt

Figures & data

Table 1 Demographic and Clinical Data of Included Infants

Number of infants	240
Gender	Male 132 (55%)
	Female 108 (45%)
Gestational age	26–39 weeks (33.25±2.74)
Birth weight	820–5500 g (1955.23±692.43)
Multiple pregnancies	26 total
	21 twins
	5 triplets
Without ROP	158 infants (65.8.1%)
With ROP	82 infants (34.1%)
	Stage 1: 10
	Stage 2: 22
	Stage 3: 35
	Stage 4a: 1
	Stage 5: 0
	APROP: 11
	Pre-plus with immature vascularization: 3
ROP not requiring treatment (mild ROP)	19 infants (7.9%)
Type 1 ROP	63 infants (26.3%)
Aggressive posterior ROP	11 infants (4.6%)

Abbreviations: ROP, retinopathy of prematurity; APROP, aggressive posterior retinopathy of prematurity.

Table 2 ROP Subgroups in Relation with BW

BW	No ROP	ROP	Mild ROP	Type 1 ROP
<1000 g (n=2)	1	1 (50%)	0	1
1000–1250 g (n=28)	12	16 (57%)	2	14
1251–1500 g (n=52)	24	28 (53.8%)	3	25
1501–2000 g (n=67)	41	26 (38.8%)	7	19
>2000 g (n=91)	80	11 (12%)	7	4

Abbreviations: BW, birth weight; ROP, retinopathy of prematurity.

Table 3 ROP Subgroups in Relation with GA

GA	No ROP	ROP	Mild ROP	Type 1 ROP
<28 weeks (5)	3	2 (40%)	0	2
28–31 weeks (60)	23	37 (61.6%)	6	31
≥32 weeks (175)	132	43 (24.5%)	13	30

Abbreviations: GA, gestational age; ROP, retinopathy of prematurity.

Table 4 Risk Factors Evaluated for an Association with the Development of ROP

Risk Factors	OR	95CI%
Birth weight equal or less than 1500 g	4.12	2.3–7.3
Gestational age equal or less than 32 weeks	6.8	3.7–12.3
Apnea	15.6	8.05–30.2
Nasal cannula	3.95	1.14–13.7
CPAP	18.9	5.7–62.7
Mechanical ventilation	13.6	5.6–33.1
Sepsis	1.1	5.6–2.17
Thrombocytopenia	2	0.6–6.5
Blood transfusion	1.15	0.5–2.5
Exchange transfusion	0.9	0.08–10.9
Phototherapy	2.1	1.2–3.7

Abbreviations: OR, odds ratio; CI, confidence interval.