https://orcid.org/0000-0001-8060-8750
Figures & data
Figure 1 Study design.
Figure 2 Predictive accuracy of corneal power measurements performed after cyclosporine was significantly higher than when performed before cyclosporine (N = 64, P < 0.03, paired t-test).
Figure 3 Significantly more patients had improvement than a decline in RMS HOA after 28 days of cyclosporine (N=64, P < 0.0001, McNemar’s Chi-squared test).
Figure 4 SPEED scores improved significantly after 28 days of treatment with cyclosporine (P < 0.00001, paired t-test).
Figure 5 Corneal staining (Oxford Scale) was measured before and after 28 days of treatment with cyclosporine and improved significantly following treatment, disappearing in 56% of patients (P<0.000001, paired t-test). Note all eyes (N=64) had at least grade 1 staining before treatment as a condition of enrolling in the study.
Figure 6 Tear breakup time was measured before and after 28 days of treatment with cyclosporine and improved significantly following treatment (N=64, P<0.00001, paired t-test).
Table 1 Conjunctival Erythema Before and After Treatment with Cyclosporine