The Effect of Age, Postoperative Refraction, and Pre- and Postoperative Pupil Size on Halo Size and Intensity in Eyes Implanted with a Trifocal or Extended Depth-of-Focus Lens

Figures & data

Table 1 Patients’ Clinical Characteristics

	Symfony (n=80)	PanOptix (n=80)
Age (years)	74.1±5.7 (58−83)	74.1±5.6 (58−84)
Sex (Female)	42%	43%
Preoperative photopic pupil size (mm)	3.26±0.3 (2.72−4.00)	3.23±0.28 (2.63−3.99)
Preoperative refraction (D)	−0.11±1.57 (−4.25−3.00)	−0.10±1.58 (−3.50−2.50)
Postoperative photopic pupil size (mm)	3.01±0.28 (2.51−3.71)	3.00±0.26 (2.43−3.70)
Postoperative refraction (D)	−0.02±0.38 (−0.75−0.50)	−0.02±0.36 (−0.75−0.50)

Abbreviation: D, diopters.

Table 2 Time Trends in Postoperative Halo Size at 1, 3, and 6 Months

Lens	Halo Size Post Operation			*P1M-3M	*P3M-6M	*P(1M-3M)-(3M-6M)
	1M	3M	6M
Symfony	3.73 ± 2.03	3.46 ± 1.84	2.90 ± 1.87	<0.001	<0.001	<0.001
PanOptix	4.60 ± 1.80	4.40 ± 1.79	3.20 ± 1.54	<0.001	<0.001	<0.001
*Wilcoxon signed-rank test

Notes: P_1M-3M: P 1M vs 3M, P_3M-6M: P 3M vs 6M, P_{(1M-3M)-(3M-6M):} between 1M and 3M vs between 3M and 6M.

Abbreviations: 1M, 1 month; 3M, 3 months; 6M, 6 months.

Table 3 Time Trends in Postoperative Halo Intensity at 1, 3, and 6 Months

Lens	Halo Intensity Post Operation			P1M-3M	P3M-6M	P(1M-3M)-(3M-6M)
	1M	3M	6M
Symfony	4.28 ± 1.79	4.09 ± 1.74	3.41 ± 1.69	<0.001	<0.001	<0.001
PanOptix	3.93 ± 1.51	3.71 ± 1.34	2.50 ± 1.19	<0.001	<0.001	<0.001

Notes: P_1M-3M: P 1M vs 3M, _P3M-6M: P 3M vs 6M, P_{(1M-3M)-(3M-6M)}: between 1M and 3M vs 3M and 6M.

Abbreviations: 1M, 1 month; 3M, 3 months; 6M, 6 months.

Figure 1 Correlation between the preoperative pupil size and halo size, measured 6 months postoperatively, with the Symfony (A) and PanOptix (B) intraocular lenses.

Abbreviation: M, month.

Figure 2 Correlation between the postoperative pupil size and halo size, measured 6 months postoperatively, with the Symfony (A) and PanOptix (B) intraocular lenses.

Abbreviation: M, month.

Figure 3 Correlation between postoperative refraction and halo size, measured 6 months postoperatively, with the Symfony (A) and PanOptix (B) intraocular lenses.

Abbreviations: M, month; SE, spherical equivalent; D, diopters.

Figure 4 Correlation between the degree of refractive correction and the degree of the decrease in halo size, measured 6 months postoperatively, with the Symphony (A) and PanOptix (B) intraocular lenses.

Abbreviation: D, diopters.

Figure 5 Correlation between age and halo size, measured 6 months postoperatively, with the Symfony (A) and PanOptix (B) intraocular lenses.

Abbreviation: M, month.

Figure 6 Correlation between preoperative and postoperative pupil size with the Symfony (A) and PanOptix (B) intraocular lenses.

Figure 7 Correlation between postoperative pupil size and postoperative refraction with the Symfony (A) and PanOptix (B) intraocular lenses.

Abbreviations: SE, spherical equivalent; D, diopters.

Figure 8 Correlation between age and postoperative pupil size with the Symfony (A) and PanOptix (B) intraocular lenses.

Figure 9 Correlation between age and postoperative refraction with the Symfony (A) and PanOptix (B) intraocular lenses.

Abbreviations: SE, spherical equivalent; D, diopters.

Figure 10 Level of discomfort due to the postoperative halo overall and with the Symfony and PanOptix intraocular lenses (A) 6 months postoperatively, where: 0 = not at all, 1 = a little, 2 = somewhat, 3 = very much, 4 = extreme. Correlation between level of discomfort and halo size measured 6 months postoperatively in the Symfony (B) and PanOptix (C) groups.