Treatment of Corneal Irregularity in Radial/Astigmatic Keratotomy Patients Utilizing WaveLight Contoura

Figures & data

Table 1 Refractive Parameters

Values in Diopters	Pre-Op Average	Range	Post-Op Average	Range
K1	37.94	33.7–42.3	38.13	32.2–44.2
K2	40.40	37.6–45.6	39.82	34.6–46.5
K Mean	39.17	35.8–42.9	38.97	33.7–45.3
K Max	47.37	42.3–56.5	45.78	39.6–52.9
Manifest Cylinder	−2.40	0 to −8	−0.32	0 to −1.75
Measured Cyl.	−3.18	−0.14 to −10.97	−1.13*	−0.08 to −6.04

Note: *5 eyes did not have sufficient quality post-op scans to determine a reliable-measured astigmatism value, HOA, or Grouped values.

Table 2 Zernicke Polynomials

Values in Microns	Pre-Op Average	Range	Post-Op Avg.	Range	% Reduction
HOA (all eyes)	1.088	0.138–2.842	0.517*	0.128–1.385	52.5%
Grouped	1.394	0.346–3.740	0.745*	0.241–2.168	46.6%

Note: *5 eyes did not have sufficient quality post-op scans to determine a reliable measured astigmatism value, HOA, or Grouped values.

Table 3 Case 1 OD: 54-Year-Old Male S/P RK in Both Eyes

Case 1 Right Eye (OD)	Manifest	BCVA	Contoura- Measured Astigmatism	T-Cat Laser Treatment	WFO Enhancement 6 Month Post-Op
Pre-Op	+2.75, −8.00 X 94	20/40	−10.97 X 78	+0.00, −3.00 X 78	+2.50, −6.00 X 80
Post-OP	PLANO	20/20	−1.06, −0.62 X 001	N/A	PLANO

Table 4 Case 1 OD: 54-Year-Old Male S/P RK in Both Eyes

Case 1 Right Eye (OD)	KMAX	HOA	HOA Grouped
PRE-OP	54.8	2.741	3.740
Post-Op	45.8	0.644	0.611
Change	9	76.5% reduction	83.7% reduction

Table 5 Case 1 OS: 54-Year-Old Male S/P RK in Both Eyes

Case 1 Left Eye (OS)	Manifest	BCVA	Contoura- Measured Astigmatism	T-Cat Laser Treatment	WFO Enhancement 6 Month Post-Op
Pre-Op	+3.00, −8.00 X 91	20/40	−10.96 X 102	+0.00, −3.00 X 91	+5.00, −9.00 X 100
Post-OP	PLANO	20/20	N/A	N/A	PLANO

Table 6 Case 1 OS: 54-Year-Old Male S/P RK in Both Eyes

Case 1 Left Eye (OS)	KMAX	HOA	HOA Grouped
PRE-OP	56.5	2.049	3.4
Post-Op	45.9	0.759	0.741
Change	10.6	63% reduction

Figure 1 (A–C) Case 1, right eye. Pre-op Topolyzer/Pentacam pachymetry/Post-op Topolyzer.

Figure 2 (A and B) Case 1, right eye. Pre-op optical coherence tomography (OCT)/Post-op OCT.

Figure 3 (A–C) Case 1, left eye. Pre-op Topolyzer/Pentacam pachymetry/Post-op Topolyzer.

Table 7 Case 2 OD: 69-Year-Old Female S/P RK in Both Eyes

Case 2 Right Eye (OD)	Manifest	BCVA	Contoura- Measured Astigmatism	T-Cat Laser Treatment	WFO Enhancement 3 Month Post-Op	WFO Enhancement 16 Month Post-Op
Pre-Op	+0.50, −1.75 X 115	20/25	−1.97 X 159	−1.97 X 159	−0.50, −0.50 X 180	plano, −0.75 X 90
Post-OP	PLANO	20/25	+0.11, −1.00 X 176	N/A	N/A	N/A

Table 8 Case 2 OD: 69-Year-Old Female S/P RK in Both Eyes

Case 2 Right Eye (OD)	KMAX	HOA	HOA Grouped
PRE-OP	44.7	0.628	0.856
Post-Op	43.1	0.128	0.339
Change	1.6	79.6% reduction

Table 9 Case 2 OS: 69-Year-Old Female S/P RK in Both Eyes

Case 2 Left Eye (OS)	Manifest	BCVA	Contoura- Measured Astigmatism	T-Cat Laser Treatment	WFO Enhancement 16 Month Post-Op
Pre-Op	+1.50, −2.00 X 20	20/40	−2.13 X 24	−2.13 X 24	+0.25, −1.00 X 105
Post-OP	−1.50, −0.50 X 050 and 20/30	20/40	−0.74, −1.14 X 173	N/A	N/A

Table 10 Case 2 OS: 69-Year-Old Female S/P RK in Both Eyes

Case 2 Left Eye (OS)	KMAX	HOA	HOA Grouped
PRE-OP	44.9	0.604	0.911
Post-Op	43.3	0.189	0.319
Change	1.6	68.7% reduction	65% reduction

Table 11 Case 3 OD: 66-Year-Old Male S/P RK in Both Eyes

Case 3 Right Eye (OD)	Manifest	BCVA	Contoura- Measured Astigmatism	T-Cat Laser Treatment	WFO Enhancement 3 Month Post-Op	WFO Enhancement 10 Month Post-Op
Pre-Op	+3.75, −1.75 X 75	20/20	−0.60 X 94	−0.60 X 94	+3.00	−1.00
Post-OP	PLANO	20/20	−0.68, −0.38 X 94	N/A	N/A	N/A

Table 12 Case 3 OD: 66-Year-Old Male S/P RK in Both Eyes

Case 3 Right Eye (OD)	KMAX	HOA	HOA Grouped
PRE-OP	42.4	0.470	0.696
Post-Op	43.3	0.354	0.529
Change	0.9	24.6% reduction	24% reduction

Table 13 Case 3 OS: 66-Year-Old Male S/P RK in Both Eyes

Case 3 Left Eye (OS)	Manifest	BCVA	Contoura- Measured Astigmatism	T-Cat Laser Treatment	WFO Enhancement 3 Month Post-Op
Pre-Op	+4.25, −1.75 X 81	20/25	−0.14 X 116	−0.14 X 116	+2.75, −0.75 X 90
Post-OP	−0.25, −0.25 X 135	20/25	+0.37, −0.74 X 177	N/A	N/A

Table 14 Case 3 OS: 66-Year-Old Male S/P RK in Both Eyes

Case 3 Left Eye (OS)	KMAX	HOA	HOA Grouped
PRE-OP	44.5	0.662	0.528
Post-Op	46.1	0.133	0.327
Change	1.6	80% reduction	38% reduction

Table 15 Case 4 OD: 67-Year-Old Male S/P RK in Both Eyes

Case 4 Right Eye (OD)	Manifest	BCVA	Contoura- Measured Astigmatism	T-Cat Laser Treatment	WFO Enhancement 3 Month Post-Op	WFO Enhancement 7 Month Post-Op
Pre-Op	+5.00, −3.75 X 75	20/25	−3.49 X 78	−3.00 X 78	+2.00, −2.25 X110	+1.25, −1.25 X 165
Post-OP	PLANO	20/25	−0.19, −0.71 X 79	N/A	N/A	N/A

Table 16 Case 4 OD: 67-Year-Old Male S/P RK in Both Eyes

Case 4 Right Eye (OD)	KMAX	HOA	HOA Grouped
PRE-OP	44.2	1.384	1.443
Post-Op	44.9	0.561	0.688
Change	0.7	59.5% reduction	52.3% reduction

Table 17 Case 4 OS: 67-Year-Old Male S/P RK in Both Eyes

Case 4 Left Eye (OS)	Manifest	BCVA	Contoura- Measured Astigmatism	T-Cat Laser Treatment	WFO Enhancement 3 Month Post-Op
Pre-Op	+3.00, −3.00 X 80	20/25	−2.22 X 87	−2.00 X 87	+1.00, −0.75 X 40
Post-OP	−1.00 GOAL -1.50	20/25	+0.12, −1.60 X 103	N/A	N/A

Table 18 Case 4 OS: 67-Year-Old Male S/P RK in Both Eyes

Case 4 Left Eye (OS)	KMAX	HOA	HOA Grouped
PRE-OP	44.6	0.815	1.026
Post-Op	43.8	0.519	0.653
Change	0.8	36.3% reduction	36.35% reduction

Table 19 Case 5 OD: 61-Year-Old Female S/P RK in Both Eyes

Case 5 Right Eye (OD)	Manifest	BCVA	Contoura- Measured Astigmatism	T-Cat Laser Treatment
Pre-Op	−1.00 D/S	20/50	−0.95 X 176	+0.00, −0.95 X 176
Post-OP	PLANO	20/40	+2.09, −1.76 X 031	N/A

Table 20 Case 5 OD: 61-Year-Old Female S/P RK in Both Eyes

Case 5 Right Eye (OD)	KMAX	HOA	HOA Grouped
PRE-OP	48.4	1.280	1.252
Post-Op	39.6	0.414	0.661
Change	8.8	67.6% reduction	47.2% reduction

Table 21 Case 5 OS: 61-Year-Old Female S/P RK in Both Eyes

Case 5 Left Eye (OS)	Manifest	BCVA	Contoura- Measured Astigmatism	T-Cat Laser Treatment
Pre-Op	+1.00, −2.25 X 007	20/50	−3.89 X 006	+0.00, −3.00 X 006
Post-OP	+1.00	20/40	−0.17, −0.11 X 12	N/A

Table 22 Case 5 OS: 61-Year-Old Female S/P RK in Both Eyes

Case 5 Left Eye (OS)	KMAX	HOA	HOA Grouped
PRE-OP	49.1	1.459	1.573
Post-Op	48.7	0.760	0.941
Change	0.4	47.9% reduction	40.2% reduction

Figure 4 (A and B) Case 1, left eye. Pre-op OCT/post-op OCT.

Figure 5 (A–C) Case 2, right eye. Pre-op Topolyzer/Pentacam pachymetry/Post-op Topolyzer.

Figure 6 (A and B) Case 2, right eye. Pre-op OCT/Post-op OCT.

Figure 7 (A–C) Case 2, left eye. Pre-op Topolyzer/Pentacam pachymetry/Post-op Topolyzer.

Figure 8 (A and B) Case 2, left eye. Pre-op OCT/Post-op OCT.

Figure 9 (A–C) Case 3, right eye. Pre-op Topolyzer/Pentacam pachymetry/Post-op Topolyzer.

Figure 10 Case 3, right eye. Post-op OCT.

Figure 11 (A–C) Case 3, left eye. Pre-op Topolyzer/Pentacam pachymetry/Post-op Topolyzer.

Figure 12 Case 3, left eye. Post-op OCT.

Figure 13 (A–C) Case 4, right eye. Pre-op Topolyzer/Pentacam pachymetry/Post-op Topolyzer.

Figure 14 Case 4, right eye. Post-op OCT.

Figure 15 (A–C) Case 4, left eye. Pre-op Topolyzer/Pentacam pachymetry/Post-op Topolyzer.

Figure 16 Case 4, left eye. Post-op OCT.

Figure 17 (A–C) Case 5, right eye. Pre-op Topolyzer/Pentacam pachymetry/Post-op Topolyzer.

Figure 18 (A and B) Case 5, right eye. Pre-op OCT/ Post-op OCT.

Figure 19 (A–C) Case 5, left eye. Pre-op Topolyzer/Pentacam pachymetry/Post-op Topolyzer.

Figure 20 (A and B) Case 5, left eye. Pre-op OCT/Post-op OCT.