Comparison of Posterior Hyaloid Assessment Using Preoperative Optical Coherence Tomography and Intraoperative Triamcinolone Acetonide Staining During Vitrectomy

Figures & data

Table 1 Patient Demographics and Previous Ocular History

		n	Percentage
Age (mean ±SD)		106	52.73 ± 12.86
Gender	Male	55	51.9
	Female	51	48.1
Eye involved	Right	59	55.7
	Left	47	44.3
Surgeon	Consultant	59	55.7
	Fellow	47	44.3

Table 2 Retinal Pathology for Surgical Indication of Vitrectomy

	n	Percentage
RRD	32	30.2
TRD	41	38.7
VH	10	9.4
VMT	3	2.8
ERM	4	3.8
FTMH	14	13.2
DLM	2	1.9

Abbreviations: RRD, rhegmatogenous retinal detachment; TRD, tractional retinal detachment; VH, vitreous haemorrhage; VMT, vitreomacular traction; ERM, epiretinal membrane; FTMH, full-thickness macular hole; DLM, Dropped Lens Material.

Table 3 Quality of OCT Results Among Study Participants

	Frequency	Percentage
PVD present	30	28.3
PVD absent	32	30.2
PVD could not be assessed (poor image quality)	44	41.5
Total	106

Abbreviation: PVD, posterior vitreous detachment.

Table 4 Status of Posterior Hyaloid After TA Staining

	Frequency	Percentage
Detachment present	30	28.3
Detachment absent	76	71.7
Total	106	100

Table 5 Overall Sensitivity and Specificity of Optical Coherence Tomography versus Triamcinolone Staining

		Triamcinolone Staining (Gold Standard)
		PVD Present	PVD Absent	Total
OCT findings	PVD present	15 (83.3%)	15 (34.1%)	30
	PVD absent	3 (16.7%)	29 (65.9%)	32
	Total	18 (100%)	44 (100%)	62

Notes: Sensitivity = 83.3%; specificity = 65.9%; positive predictive value = 43.56%; negative predictive value = 92.6; assuming a disease prevalence of 24%.

Abbreviations: PVD, posterior vitreous detachment; OCT, optical coherence tomography.

Figure 1 OCT image of a case labelled as Grade 4 PVD on OCT (A), but intraoperative TA staining determined a posterior hyaloid attachment (false-positive). Case (B) was labelled to have Grade 3 OCT (attached to the optic nerve head) although intraoperative staining showed that a complete PVD was present (false-negative).