One-Year Outcomes of Intracorneal Ring–Segment Insertion Assisted by Femtosecond Laser Simultaneously Performed with Corneal Collagen Cross-Linking for Treatment of Keratoconus

Figures & data

Table 1 Pre- and postoperative outcomes

		Follow-up
		Preop	3 months	6 months	1 year
UAVA (logMAR)	Mean ± SD	0.649±0.239	0.514±0.222	0.419±0.162	0.379±0.142
	Range (P)	0.3–1.3	0.18–1.3 (0.014*)	0.1–0.78 (<0.001*)	0.1–0.6 (<0.001*)
BCVA (logMAR)	Mean ± SD	0.326±0.144	0.348±0.151	0.279±0.124	0.231±0.140
	Range (P)	0.1–0.6	0–0.6 (0.283)	0–0.48 (0.088)	0–0.48 (0.006*)
SE (D)	Mean ± SD	−3.45±2.31	−2.69±1.85	−2.42±1.73	−2.11±1.84
	Range (P)	−8.0 to 0.5	−6.5 to 0.75 (0.194)	−6.5 to 0.5 (0.0298*)	−6 to 2 (0.0081*)
Refractive astigmatism (D)	Mean ± SD	4.7±1.6	3.5±1.3	2.9±1.2	2.6±1.1
	Range (P)	1.3–8.0	1.5–7.5 (0.002*)	1.0–7.5 (<0.001*)	0.8–6.0 (<0.001*)
Flattest K (D)	Mean ± SD	47.30±3.6	46.43±3.27	46.18±2.95	45.85±3.46
	Range (P)	40–54.7	39.3−54.9 (0.168)	39−53.4 (0.097)	39−53.2 (0.061)
Steepest K (D)	Mean ± SD	51.89±3.81	50.32±4.49	49.87±4.57	49.40±4.39
	Range (P)	45.2–59.5	42.1–59 (0.074)	41.8−60.2 (0.034*)	42.3–60.9 (0.011*)
Kmax (D)	Mean ± SD	57.73±5.92	57.16±6.52	56.21±6.49	55.83±5.94
	Range (P)	47.1–68.2	46.8−69.9 (0.362)	45.1−68.6 (0.173)	46−67.2 (0.109)
Keratometric astigmatism (D)	Mean ± SD	4.6±1.8	3.7±1.8	3.9±1.9	3.5±1.6
	Range (P)	0.5–7.7	0.1–6.3 (0.041*)	0.4–7.9 (0.073)	0.4–6.2 (0.010*)
Thickness (µm)	Mean ± SD	434.90±40.50	411.77±43.26	419.67±41.73	424.67±44.23
	Range (P)	362–520	351–488 (0.018*)	345–512 (0.078)	339–512 (0.177)

Note: *Statistically significant.

Abbreviations: BCVA, best-corrected visual acuity; UAVA, unaided visual acuity.

Table 2 Pre- and postoperative log contrast sensitivity

	Follow-up	Row A (3 cpd)	Row B (6 cpd)	Row C (12 cpd)	Row D (18 cpd)
Mean ± SD Range (P)	Preop	1.13±0.37	1.40±0.31	1.05±0.35	0.65±0.29
		0.4–1.63	0.61–1.99	0.31–1.69	−0.13 to 1.25
	3 months	1.19±0.33	1.55±0.30	1.13±0.39	0.77±0.35
		0.4–1.63 (0.253)	0.91–1.99 (0.035*)	0.31–1.99 (0.202)	0.17–1.4 (0.065)
	6 months	1.32±0.37	1.58±0.24	1.21±0.35	0.77±0.27
		0.7–2.08 (0.241)	0.91–1.99 (0.009*)	0.61–1.84 (0.036*)	0.17–1.25 (0.046*)
	1 year	1.26±0.41	1.54±0.26	1.18±0.37	0.79±0.21
		0.4–1.93 (0.099)	0.91–1.99 (0.032*)	0.31–1.99 (0.032*)	0.47–1.25 (0.018*)

Note: *Statistically significant.