Preliminary Clinical Outcomes of a New Enhanced Depth of Focus Intraocular Lens

Figures & data

Table 1 Demographic and Biometric Data

	LuxSmart	Akreos	p-value
Number of Patient/Eyes (n)	12/24	12/24	–
Female (%)	50%	50%	–
Age (y) ± SD	68 ± 6.7	71 ± 5.4	0.42
Axial length (mm) ± SD	23.3 ± 0.7	22.8 ± 0.8	0.31
K1 (D) ± SD	43.6 ± 1.1	44.1 ± 0.9	0.42
K2 (D) ± SD	44.3 ± 1.3	44.5 ± 1.2	0.52
IOL power (D) ± SD	21.9 ± 1.3	22.3 ±1.1	0.33

Abbreviations: SD, Standard deviation; K1, Flat corneal meridian; K2, Steep corneal meridian; D, Diopters; IOL, Intraocular lens.

Table 2 Clinical Outcomes

Clinical Outcomes (3 Months)		LuxSmart	Akreos	p-value
Binocular Snellen (logMAR)	CDVA	20/20 (−0.08 ± 0.04)	20/20 (−0.02 ± 0.07)	0.52
	UDVA	20/20 (0.02 ± 0.11)	20/20 (0.01 ± 0.10)	0.71
	UIVA	20/32 (0.18 ± 0.12)	20/40 (0.30 ± 0.13)	<0.001
	UNVA	20/32 (0.38 ± 0.14)	20/40 (0.44 ± 0.17)	0.02
Monocular Snellen (logMAR)	CDVA	20/20 (−0.04 ± 0.01)	20/20 (−0.01 ± 0.03)	0.66
	UDVA	20/22 (0.10 ± 0.11)	20/25 (0.01 ± 0.15)	0.62
	UIVA	20/32 (0.21 ± 0.08)	20/40 (0.36 ± 0.13)	<0.001
Spherical Equivalent, (D)		−0.08 ± 0.4	−0.12 ± 0.5	0.37

Note: Significant statistic difference is highlighted by p-values in bold.

Abbreviations: logMAR, Logarithm of minimum angle of resolution; D, Diopters.

Figure 1 Monocular distance-corrected defocus curve three months after binocular implantation of IOL.

Abbreviations: IOL, Intraocular lens; logMAR, Logarithm of minimum angle of resolution; D, Diopters.

Table 3 Incidence of Photic Phenomena

Photic Phenomena	Halos			Glare
	LuxSmart	Akreos	p-value	LuxSmart	Akreos	p-value
Never	8 (66.7%)	8 (66.7%)		8 (66.7%)	8 (66.7%)	0.66
Rarely	2 (16.7%)	2 (16.7%)		3 (25%)	4 (33.3%)
Sometimes	1 (8.3%)	1 (8.3%)	0.89	1 (8.3%)	0 (0%)
Often	1 (8.3%)	1 (8.3%)		0 (0%)	0 (0%)
Always	0 (0%)	0 (0%)		0 (0%)	0 (0%)

Table 4 Results of Catquest 9-SF (Uncorrected Vision)

		LuxSmart	Akreos	p-value
		n (%)	n (%)
Reading newspaper print	Yes, very great difficulty	2	5
	Yes, great dificulty	2	4
	Yes, some difficulty	2	2	0.01
	No, no difficulty	6	1
	Cannot decide	0	0
Recognizing the faces of people	Yes, very great difficulty	0	0
	Yes, great dificulty	0	0
	Yes, some difficulty	1	1	0.52
	No, no difficulty	11	11
	Cannot decide	0	0
Reading the prices of goods while shopping	Yes, very great difficulty	0	9
	Yes, great dificulty	0	2
	Yes, some difficulty	2	1	0.001
	No, no difficulty	10	0
	Cannot decide	0	0
Seeing to walk on uneven ground	Yes, very great difficulty	0	0
	Yes, great dificulty	0	0
	Yes, some difficulty	1	1	0.66
	No, no difficulty	11	11
	Cannot decide	0	0
Reading television text	Yes, very great difficulty	0	0
	Yes, great dificulty	1	2
	Yes, some difficulty	1	1	0.52
	No, no difficulty	10	9
	Cannot decide	0	0
Seeing to use the computer	Yes, very great difficulty	0	4
	Yes, great dificulty	1	4
	Yes, some difficulty	3	2	0.001
	No, no difficulty	8	2
	Cannot decide	0	0
Difficulties in performing everyday tasks	Yes, very great difficulty	0	0
	Yes, great dificulty	0	0
	Yes, some difficulty	5	10	0.07
	No, no difficulty	7	2
	Cannot decide	0	0
Satisfied or dissatisfied with your present vision	Very satisfied	10	6
	Rather satisfied	2	5
	Rather dissatisfied	0	1	0.04
	Very dissatisfied	0	0

Note: Significant statistic difference is highlighted by p-values in bold.