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Case Series

Efficacy of repeated 5-fluorouracil needling for failing and failed filtering surgeries based on simple gonioscopic examination

Pages 15-22 | Published online: 28 Dec 2012

Figures & data

Figure 1 Flat vascularized failing bleb of eye 5 before needling.

Figure 1 Flat vascularized failing bleb of eye 5 before needling.

Figure 2 Less-vascularized failing, elevated bleb after first needling and 5-FU injection.

Figure 2 Less-vascularized failing, elevated bleb after first needling and 5-FU injection.

Figure 3 Preoperative serial field examination of eye 1 with advanced disease.

Figure 3 Preoperative serial field examination of eye 1 with advanced disease.

Figure 4 Preoperative serial optical coherence tomography examination of eye 1 with advanced disease.

Figure 4 Preoperative serial optical coherence tomography examination of eye 1 with advanced disease.

Figure 5 Two successive preoperative field examinations of eye 4 with advanced disease.

Figure 5 Two successive preoperative field examinations of eye 4 with advanced disease.

Figure 6 Two preoperative serial optical coherence tomography examinations for retinal nerve fiber layer progression of eye 4.

Figure 6 Two preoperative serial optical coherence tomography examinations for retinal nerve fiber layer progression of eye 4.

Table 1 Descriptive statistics of needling and 5-fluorouracil (5-FU) injection

Table 2 Comparison between preneedling and postneedling intraocular pressure (IOP) and medications

Table 3 Comparison between postoperative IOP of failing versus failed groups, and episcleral fibrosis versus intrascleral fibrosis groups

Table 4 Correlation between postneedling IOP and number of needlings and injections

Figure 7 Kaplan–Meier curve of time to achieve target IOP.

Figure 7 Kaplan–Meier curve of time to achieve target IOP.