Academy IRIS^® Registry Analysis of Incidence of Laser Capsulotomy Due to Posterior Capsule Opacification After Intraocular Lens Implantation

Figures & data

Table 1 Demographics and Baseline Characteristics of Master Cohort

Characteristic	AcrySof (n=47,930)	Tecnis (n=42,017)	Total (N=89,947)
Age, mean (SD), y	71.3 (8.1)	68.6 (7.7)^a	70.0 (8.0)
Sex, n (%)
Female	29,400 (61.3)	25,275 (60.2)^a	54,675 (60.8)
Male	18,530 (38.7)	16,742 (39.8)	35,272 (39.2)
Race, n (%)
White	39,004 (81.4)	34,899 (83.1)^a	73,903 (82.2)
Black	3364 (7.0)	1292 (3.1)	4656 (5.2)
Other or not reported	5562 (11.6)	5826 (13.9)	11,388 (12.7)
Region, n (%)
Midwest	13,697 (28.6)	8568 (20.4)^a	22,265 (24.8)
North	5769 (12.0)	3955 (9.4)	9724 (10.8)
South	22,792 (47.6)	22,616 (53.8)	45,408 (50.5)
West	5672 (11.8)	6878 (16.4)	12,550 (14.0)
IOL type, n (%)
Monofocal	40,611 (84.7)	8447 (20.1)^a	49,058 (54.5)
Monofocal toric	5515 (11.5)	2950 (7.0)	8465 (9.4)
Diffractive multifocal	1675 (3.5)	5105 (12.1)	6780 (7.5)
Diffractive multifocal toric	129 (0.3)	–	129 (0.3)
Diffractive EDOF	–	18,521 (44.1)	18,521 (44.1)
Diffractive EDOF toric	–	6994 (16.6)	6994 (16.6)

Note: ^aP<0.001.

Abbreviations: EDOF, extended depth of focus; IOL, intraocular lens.

Table 2 Demographics and Baseline Characteristics of Patients with a Diagnosis of PCO^a After Cataract Surgery

Characteristic	1-Year Follow-Up (N=24,834)
Age, mean (SD), y	68.9 (7.7)
Sex, n (%)
Female	15,815 (63.7)
Male	9019 (36.3)
Race, n (%)
White	21,044 (84.7)
Black	775 (3.1)
Other or not reported	3015 (12.1)
Region, n (%)
Midwest	5233 (21)
North	2452 (10)
South	12,420 (50)
West	4729 (19)

Note: ^aPCO was defined as the presence of a PCO diagnosis code (ICD-10 code H26.491 or H26.492 or H26.493 or H26.499) within 365 days of the cataract procedure.

Abbreviations: ICD-10, International Classification of Diseases, 10th revision; PCO, posterior capsular opacification.

Figure 1 Incidence of Nd:YAG due to PCO (A) by type and (B) by brand of IOL. Nd:YAG laser capsulotomy due to PCO was defined as the presence of an Nd:YAG procedure code (CPT 66821) with an accompanying PCO diagnosis code (ICD-10 code H26.491 or H26.492 or H26.493 or H26.499) for the same eye on the date of the Nd:YAG procedure or between the Nd:YAG procedure and the cataract procedure.

Abbreviations: CPT, current procedural terminology; EDOF, extended depth of focus; ICD-10, International Classification of Diseases, 10th revision; IOL, intraocular lens; PCO, posterior capsular opacification; Nd:YAG, neodymium-doped yttrium aluminum garnet.

Figure 2 Risk of Nd:YAG due to PCO by IOL type or brand, baseline characteristics, and region. Nd:YAG laser capsulotomy due to PCO was defined as the presence of an Nd:YAG procedure code (CPT 66821) with an accompanying PCO diagnosis code (ICD-10 code H26.491 or H26.492 or H26.493 or H26.499) for the same eye on the date of the Nd:YAG procedure or between the Nd:YAG procedure and the cataract procedure.

Abbreviations: CPT, current procedural terminology; EDOF, extended depth of focus; ICD-10, International Classification of Diseases, 10th revision; IOL, intraocular lens; OR, odds ratio; PCO, posterior capsular opacification; Nd:YAG, neodymium-doped yttrium aluminum garnet.

Figure 3 Time to PCO diagnosis (A) by type and (B) by brand. PCO was defined as the presence of a PCO diagnosis code (ICD-10 code H26.491 or H26.492 or H26.493 or H26.499) within 365 days of the cataract procedure.

Abbreviations: ICD-10, International Classification of Diseases, 10th revision; PCO, posterior capsular opacification.

Figure 4 Time to Nd:YAG diagnosis (A) by type and (B) by brand. Nd:YAG was defined as the presence of an Nd:YAG procedure code (CPT code 66821) within 365 days of the cataract procedure.

Abbreviations: CPT, current procedural terminology; Nd:YAG, neodymium-doped yttrium aluminum garnet.