Clinical Characteristics of Idiopathic Orbital Inflammation Syndrome in Relation to Intraocular Pressure

Figures & data

Table 1 Clinical Characteristics of the 20 Cases

Age mean±SD (range)	55.4±13.7 (32–79)
Male : female	1:19
Type
Dacryoadenitis	14/20 (47%)
Myositis	5/20 (40%)
Diffuse	3/20 (33%)
Posterior periscleritis	1/20 (20%)
Phakia: pseudophakia	19:1
Bilateral:unilateral	18:1
Biopsy performed	5/20 (25%)
Mean visual acuity (logMAR)	−0.04±0.12
Shallow anterior chamber in acute phase	1/20 (5%)

Abbreviations: MAR, minimum angle of resolution; SD, standard deviation.

Table 2 Treatment for Idiopathic Orbital Inflammation

Treatment Content	N=20
Oral steroid (PSL 50–30 mg)	16/20(80%)
Steroid pulse	1/20(5%)
Local steroid injection	3/20(15%)
Recurrence	6/20(30%)
Relapse treatment
Oral steroid	4/6(67%)
Increased steroid dose + immunosuppressant	2/6(33%)

Figure 1 Changes in IOP before and after treatment. IOP is shown on the vertical axis. After treatment, IOP decreased significantly. *p = 0.009.

Figure 2 IOP by inflammatory site. IOP is shown on the vertical axis. The type of idiopathic orbital inflammation is shown on the horizontal axis. *p < 0.05 Dacryoadenitis vs Diffuse type.

Figure 3 Percentage of high IOP before treatment by inflammation site. The percentage is shown on the vertical axis. The type of idiopathic orbital inflammation is shown on the horizontal axis.

Table 3 Ocular Symptoms Prior to Treatment of Idiopathic Orbital Inflammation

Ocular Symptoms	21 mmHg or More (N = 7)	20 mmHg or Less (N = 13)	P value
Proptosis	3/7(42%)	2/13(15%)	0.29
Ocular pain	6/7(86%)	5/13(38%)	0.07
Decreased ocular movements or diplopia	3/3(100%)	4/13(31%)	0.06
Periorbital edema	7/7(100%)	12/13(92%)	1

Notes: The P value was calculated by Fisher’s exact test.