Visual and Refractive Outcomes Following Exchange of an Opacified Multifocal Intraocular Lens

Figures & data

Figure 1 Diffusely opacified Lentis Mplus IOL prior to explantation.

Table 1 Demographics and Baseline Characteristics

	Preoperative
No. of patients (eyes)	31 (37)
Age (y), mean ± SD (range)	69 ± 9.2 (52 to 88)
Gender, male/female (%)	15/16 (48/52)
Time (y) from initial implant to exchange, mean ± SD (range)	7.1 ± 1.6 (4.1 to 9.5)
Clinical parameter, mean ± SD (range)
Sphere (D)	0.23 ± 0.62 (−0.75 to 2.00)
Cylinder (D)	−0.29 ± 0.43 (−1.50 to 0.00)
MSE (D)	0.08 ± 0.57 (−1.00 to 1.25)
UDVA (logMAR)	0.23 ± 0.20 (−0.10 to 0.80)
CDVA (logMAR)	0.13 ± 0.15 (−0.14 to 0.46)

Abbreviations: MSE, mean spherical equivalent; UDVA, unaided distance visual acuity; CDVA, corrected distance visual acuity.

Table 2 Model, Design and Implant Location of Secondary IOLs

	Location of Secondary IOL
Model/Design	Bag	Sulcus	Sulcus (+OC)	Iris
Alcon AcrySof IQ/1-piece monofocal	2	–	–	–
Zeiss CT Asphina 409MP/1-piece monofocal	1	–	–	–
Tecnis ZA9003/3-piece monofocal	–	2	1	–
Zeiss EC-3 PAL/3-piece monofocal	–	3	4	–
Zeiss CT Lucia 202/3-piece monofocal	–	6	–	–
Ophtec Artisan/Iris claw monofocal	–	–	–	2
Lenstec SBL-3/1-piece bifocal	1	–	–	–
Lentis Mplus LU-814 MF30/1-piece multifocal with 4 open loop haptics	–	6	–	–
Alcon Panoptix/1-piece multifocal	9	–	–	–
Total (n = 37)	13	17	5	2

Abbreviation: OC, optic capture.

Table 3 Visual Outcomes Following IOL Exchange

	Postoperative Visit 1		Postoperative Visit 2
Secondary IOL	Monofocal (n = 21)	Multifocal (n = 16)	Monofocal (n = 19)	Multifocal (n = 10)
Mean time to follow-up (weeks)	4.5 ± 2.3	4.1 ± 1.1	39.1 ± 25.7	30.0 ± 14.7
Sphere (D)	−0.23 ± 0.88 (−1.75 to 1.50)	−0.08 ± 0.47 (−1.00 to 0.75)	−0.31 ± 0.74 (−1.75 to 1.25)	−0.05 ± 0.63 (−1.00 to 1.25)
Cylinder (D)	−0.64 ± 0.55 (−2.25 to 0.00)	−0.58 ± 0.42 (−1.50 to 0.00)	−0.56 ± 0.50 (−1.50 to 0.00)	−0.60 ± 0.64 (−2.00 to 0.00)
MSE (D)	−0.54 ± 0.80 (−2.00 to 1.00)	−0.37 ± 0.50 (−1.13 to 0.50)	−0.58 ± 0.74 (−2.00 to 0.75)	−0.35 ± 0.62 (−1.25 to 0.75)
UDVA (logMAR)	0.20 ± 0.24 (−0.10 to 0.74)	0.16 ± 0.11 (0.00 to 0.34)	0.17 ± 0.20 (−0.10 to 0.54)	0.10 ± 0.15 (−0.06 to 0.42)
UIVA (logMAR)	–	0.33 ± 0.10 (0.20 to 0.40)	–	0.43 ± 0.06 (0.30 to 0.48)
UNVA (logMAR)	–	0.25 ± 0.10 (0.10 to 0.40)	–	0.25 ± 0.13 (0.00 to 0.48)
CDVA (logMAR)	−0.02 ± 0.08 (−0.14 to 0.20)	0.02 ± 0.08 (−0.10 to 0.12)	−0.02 ± 0.10 (−0.18 to 0.20)	−0.02 ± 0.09 (−0.18 to 0.10)

Abbreviations: UIVA, unaided intermediate visual acuity; UNVA, unaided near visual acuity.

Table 4 Refractive Outcomes Following IOL Exchange

	Multifocal to Monofocal (n = 21)	Multifocal to Multifocal (n = 16)	All (n = 37)
Mean prediction error (D) ± SD (Range)	−0.57 ± 0.67 (−2.21 to 0.60)	−0.33 ± 0.59 (−1.53 to 0.72)	−0.46 ± 0.64 (−2.21 to 0.72)
Mean absolute error (D) ± SD (Range)	0.70 ± 0.53 (0.04 to 2.21)	0.56 ± 0.37 (0.10 to 1.53)	0.64 ± 0.47 (0.04 to 2.21)

Figure 2 Lentis Mplus LU-814 MF30 IOL (image courtesy of Oculentis GmbH).