Changes in the foveal microstructure after intravitreal bevacizumab application in patients with retinal vascular disease

Figures & data

Figure 1 The foveal avascular zone was manually circumscribed on an early-phase fluorescein angiogram and the software measured the area (in mm²).

Figure 2 Box plots summarize the increase in foveal avascular zone area (mm²) at FU1 compared to pre OP measurements for all patients (overall) and the patients with DME and BRVO.

Abbreviations: BRVO, branch retinal vein occlusion; DME, diabetic macular edema; FU1, first follow-up visit; Pre OP, before injection of bevacizumab.

Table 1 Foveal avascular zone area measurements

Foveal avascular zone (mm^2)	DME		BRVO		Overall
	Pre OP	FU1	Pre OP	FU1	Pre OP	FU1
Mean	0.36	0.43	0.29	0.41	0.33	0.42
Median	0.33	0.42	0.28	0.33	0.31	0.38
First quartile	0.26	0.34	0.21	0.26	0.24	0.30
Third quartile	0.46	0.51	0.36	0.41	0.41	0.47
Minimum	0.14	0.16	0.04	0.07	0.04	0.07
Maximum	0.63	0.71	0.62	1.96	0.63	1.96
Standard deviation	0.13	0.14	0.11	0.35	0.13	0.26

Abbreviations: BRVO, branch retinal vein occlusion; DME, diabetic macular edema; FU1, first follow-up visit; Pre OP, before injection of bevacizumab.