Navigated macular laser decreases retreatment rate for diabetic macular edema: a comparison with conventional macular laser

Figures & data

Figure 1 Examples before and after laser. Two sample patients conventionally treated (patient A) or treated by Navilas^® (patient B). (A) Fluorescein angiography with treatment area marked. (B) Navilas fundus photograph with fluorescein angiography overlay and preplanned laser spots. (C) Three-month follow-up on fluorescein angiography. (D) Fluorescein angiogram with executed laser treatment spots marked by Navilas.

Table 1 Baseline patient characteristics

Variable	Navilas group (n = 46)	Conventional laser control group (after matching), n = 28	Statistical significance
Age (years)	61 ± 11.02	61 ± 11.7	P = 0.94
Gender (% female)	24%	18%	P = 0.48
Baseline visual acuity	0.48 ± 0.37	0.49 ± 0.40	P = 0.90
Laser spots planned (n)	105 ± 94	74 ± 48	P = 0.20

Figure 2 Visual acuity change over time (mean letters gained).

Note: *Indicates statistical significance.

Figure 3 Visual acuity change over time [letters gained] matched for age, gender, and baseline visual acuity but unmatched for the number of laser spots.

Note: *Indicates significant difference.

Figure 4 Kaplan-Meier analysis of retreatment rate.

Notes: After approximately 2 months, the survival curves separate, indicating more retreatments for the conventional laser group (P = 0.02). The 3-month period after first laser treatment, in which usually no retreatment is performed, is marked green.