Iatrogenic retinal breaks during 20-gauge vitrectomy for proliferative diabetic retinopathy

Figures & data

Table 1 Incidence of each type of iatrogenic break

Iatrogenic break	Group 1 (n = 259)	Group 2 (n = 318)	Group 3 (n = 183)	P-value
During membrane dissection	No dissection	67 (21.0)	91 (49.7)	<0.001*
Peripheral	21 (8.1)	19 (6.0)	17 (9.3)	0.359†
Oral dialysis	2 (0.8)	7 (2.2)	7 (3.8)	0.087†

Notes: Group 1, vitreous hemorrhage only; group 2, fibrovascular membranes requiring treatment without traction retinal detachment; group 3, fibrovascular membrane with traction retinal detachments. Eyes (%). Some eyes showed multiple types of breaks.

† mxn χ² test;

* χ² test.

Table 2 Postoperative complications

	Group 1 (n = 259)	Group 2 (n = 318)	Group 3 (n = 183)	P-value
Vitreous rebleeding	5 (1.9)	10 (3.1)	12 (6.6)	0.03†
Neovascularization at the sclerotomy site	3 (1.2)	1 (0.3)	6 (3.3)	0.019†
Retinal detachment due to reproliferation	0 (0)	6 (1.9)	15 (8.2)	<0.001*
Neovascular glaucoma	6 (2.3)	10 (3.1)	14 (7.7)	0.011†

Notes: Eyes (%). Some eyes showed multiple types of breaks.

† mxn χ² test;

* χ² test.

Table 3 Iatrogenic breaks and postoperative complications

	VH	NV	RD	NVG
Breaks during membrane dissection
OR	2.6 (1.2–5.7)	1.7 (0.42–7.3)	8.0 (3.3–19.4)	2.2 (1.0–4.8)
P-value	0.019	0.444	<0.001	0.048
Peripheral breaks
OR	1.3 (0.29–5.7)	3.9 (0.77–20.1)	1.0 (0.138.1)	1.1 (0.25–4.8)
P-value	0.737	0.100	0.986	0.910
Oral dialysis
OR	8.0 (2.3–27.5)	5.7 (0.64–50.7)	3.0 (0.59–15.0)	3.0 (0.64–14.4)
P-value	0.001	0.200	0.188	0.162

Abbreviations: VH, vitreous rebleeding; NV, neovascularization at sclerotomy site; RD, retinal detachment due to reproliferation; NVG, neovascular glaucoma; OR, odds ratio (95% confidence interval).