Photoreceptor disruption in central serous chorioretinopathy treated by half-dose photodynamic therapy

Figures & data

Figure 1 The optical coherence tomography of a patient with photoreceptor disruption demonstrated the discontinuity of the inner segment/outer segment line (arrows).

Figure 2 The optical coherence tomography of a patient with photoreceptor disruption demonstrated total absence of inner segment/outer segment line (arrow).

Table 1 Demographic data

	Data
Mean age (years ± SD)	46.24 ± 7.16
Sex (%)
Male	27 (93.1)
Female	2 (6.9)
Final BCVA (patients, %)
Improved BCVA	27 (93.1)
Stable BCVA	2 (6.9)
Presence of photoreceptor disruption at 12 months (patients, %)
Present	13 (44.8)
Absent	16 (55.2)

Abbreviations: SD, standard deviation; BCVA, best-corrected visual acuity.

Table 2 Study results

Variable	Photoreceptor disruption		P-value
	Present	Absent
Mean duration of symptoms (days ± SD)	205.00 ± 197.3	182.63 ± 260.61	0.800
Mean BCVA (logMAR ± SD)
At baseline	0.52 ± 0.35	0.20 ± 0.13	0.006
At 1 month	0.42 ± 0.37	0.10 ± 0.09	0.009
At 3 months	0.33 ± 0.35	0.04 ± 0.05	0.010
At 6 months	0.34 ± 0.38	0.03 ± 0.05	0.029
At 12 months	0.31 ± 0.34	0.01 ± 0.03	0.008
Mean BCVA improvement (logMAR ± SD)	0.22 ± 0.24	0.19 ± 0.13	0.694
Mean central macular thickness from OCT (micron ± SD)
At baseline	333.50 ± 74.25	439.00 ± 106.99	0.267
At 1 month	196.00 ± 30.61	228.00 ± 19.80	0.400
At 3 months	174.25 ± 42.72	225.00 ± 18.22	0.032
At 6 months	187.00 ± 49.19	224.70 ± 22.68	0.118
At 12 months	192.25 ± 62.02	233.71 ± 15.27	0.412
Mean central macular thickness improvement from OCT (micron ± SD)	135.00 ± 38.18	160.00 ± 118.79	1.000

Abbreviations: SD, standard deviation, BCVA, best-corrected visual acuity, logMAR, logarithm of minimum angle of resolution; OCT, optical coherence tomography.

Figure 3 The mean visual acuity changes in central serous chorioretinopathy patients with and without photoreceptor disruption treated by half-dose photodynamic therapy.

Abbreviations: BCVA, best-corrected visual acuity, logMAR, logarithm of minimum angle of resolution.