Changes in axial length and choroidal thickness after intraocular pressure reduction resulting from trabeculectomy

Figures & data

Table 1 Demographic data

Parameter	n
Number of subjects	14
Men/women	(9/5)
Age (years, mean ± SD)	65.0 ± 8.7
Glaucoma type
POAG subjects	8
Secondary glaucoma subjects	6

Abbreviations: SD, standard deviation; POAG, primary open-angle glaucoma.

Figure 1 Relationships between intraocular pressure, axial length, and choroidal thickness changes following trabeculectomy.

Notes: (A) The decreases in IOP were correlated positively with shortening of the axial length. (B) The increase in the choroidal thickness at the fovea was not correlated with either decreases in IOP or shortening of the axial length. (C) The increase in subfoveal choroidal thickness was not correlated with either decreases in IOP or shortening of the axial length. Decrease in IOP was correlated with the increases in the choroidal thickness around the optic disc inferiorly and nasally, but not superiorly and temporally. Δ, changes following trabeculectomy.
Abbreviation: IOP, intraocular pressure.

Table 2 Intraocular pressure, axial length, and choroidal thickness before and after trabeculectomy

	N	Trabeculectomy eye			Fellow eye
		Preoperatively (mean ± SD)	Postoperatively (mean ± SD)	P-value	Preoperatively (mean ± SD)	Postoperatively (mean ± SD)	P-value
IOP	14	26.6 ± 7.6	7.2 ± 2.6	<0.0001*	17 ± 4.7	15.5 ± 6.1	0.22
Axial length	14	25.12 ± 1.42	24.86 ± 1.43	<0.001*	25 ± 1.52	24.99 ± 1.52	0.62
Choroidal thickness
Fovea	14	206 ± 64	254 ± 64	<0.0001*	242 ± 51	245 ± 62	0.27
Superior to disc	10	164 ± 50	222 ± 49	<0.01*	189 ± 57	187 ± 66	0.78
Temporal to disc	10	140 ± 70	187 ± 61	<0.01*	154 ± 56	161 ± 57	0.06
Inferior to disc	10	123 ± 50	188 ± 57	<0.01*	117 ± 39	131 ± 44	0.09
Nasal to disc	10	159 ± 72	204 ± 67	<0.01*	171 ± 64	181 ± 63	0.27

Note:

* P < 0.05.

Abbreviations: N, number; SD, standard deviation; IOP, intraocular pressure.

Table 3 Relationships between intraocular pressure, axial length and choroidal thickness changes following trabeculectomy

Factor	N	Δ IOP
		Coefficient	R^2	P-value
Δ Axial length	14	0.018	0.41	0.013*
Factor	N	Δ Subfoveal choroidal thickness
		Coefficient	R^2	P-value
Δ IOP	14	0.069	0.08	0.32
Δ Axial length	14	0.0022	0.1	0.27
Δ Choroidal thickness around the optic disc	N	Δ IOP
		Coefficient	R^2	P-value
Superior	10	−0.8	0.025	0.65
Temporal	10	−2.97	0.36	0.06
Inferior	10	−3.56	0.42	0.04*
Nasal	10	−2.61	0.44	0.035*

Note:

* P < 0.05. Δ, changes following trabeculectomy.

Abbreviation: IOP, intraocular pressure.

Table 4 Total sum of axial length and subfoveal choroidal thickness before and after trabeculectomy

Trabeculectomy eye			Fellow eye
Preoperatively (mean ± SD) mm	Postoperatively (mean ± SD) mm	P-value	Preoperatively (mean ± SD) mm	Postoperatively (mean ± SD) mm	P-value
25.32 ± 1.41	25.11 ± 1.42	0.004*	25.24 ± 1.51	25.24 ± 1.53	0.83

Note:

* P < 0.05.

Abbreviation: SD, standard deviation.