Ab Interno Canaloplasty and Trabeculotomy Outcomes for Mild, Moderate, and Advanced Open-Angle Glaucoma: A ROMEO Analysis

Figures & data

Table 1 Patient Demographics and Characteristics

	Advanced (N=6)	Moderate (N=42)	Mild (N=79)
VF MD, dB, Mean (SD)	−13.3 (0.78)	−8.4 (1.60)	−2.7 (2.20)
Type of Procedure, n (%)
Standalone	3 (50)	18 (43)	27 (34)
Combined with Cataract	3 (50)	24 (57)	52 (66)
Age, Mean (SD)	76.5 (7.4)	73.6 (9.6)	71 (8.1)
Sex, n (%)
Female	4 (67)	21 (50)	42 (53)
Male	2 (33)	21 (50)	37 (47)
Race, n (%)
White	4 (66.7)	33 (78.6)	59 (74.7)
Black	0	1 (2.4)	4 (5.1)
Asian	1 (16.7)	2 (4.8)	8 (10.1)
Other	1 (16.7)	0	0
Not reported	0	6 (14.3)	8 (10.1)
Ethnicity, n (%)
Hispanic	1 (16.7)	9 (21.4)	16 (20.3)
Non-Hispanic	5 (83.3)	26 (61.9)	54 (68.4)
Not reported	0	7 (16.7)	9 (11.4)
Diagnosis, n (%)
POAG	5 (83.3)	40 (95.2)	75 (94.9)
PG	0	0	1 (1.3)
PXF	1 (16.7)	2 (4.8)	3 (3.8)
Baseline IOP, mmHg, Mean (SD)	20.0 (3.6)	17.2 (5.2)	17.1 (4.3)
Baseline number of medications, Mean (SD)	2.8 (1.6)	1.9 (1.2)	1.7 (1.3)
Secondary surgical interventions, n (%)	1 (16.7)	5 (11.9)	3 (3.8)

Figure 1 Mean IOP at Baseline (blue) and Month 12 (Orange) for Mild, Moderate and Severe groups. No significant difference between groups at Baseline or Month 12 (P = 0.213 and 0.269, respectively). * P<0.05, ** P<0.01, *** P<0.001.

Figure 2 Scatterplot of Baseline IOP (x-axis) versus Month 12 IOP (y-axis) for Mild (black circles), Moderate (red circles), Advanced (blue circles). Diagonal is the line of no change. Dashed horizontal line at 18 mmHg.

Figure 3 Scatterplot of Mean Deviation (x-axis) versus Month 12 IOP (y-axis). Dotted line is least squares regression line.

Figure 4 Mean Medications at Baseline (blue) and Month 12 (Orange) for Mild, Moderate and Severe groups. No significant difference between groups at Baseline or Month 12 (P = 0.145 and 0.161, respectively). * P<0.05, *** P<0.001. Numbers in parentheses are standard deviations.

Data Sharing Statement

The authors do not intend to share participant-level data. Other queries or requests should be directed to the corresponding author (JD).