36-Month Outcomes of Ahmed ClearPath^® Glaucoma Drainage Device in Severe Primary Open Angle Glaucoma

Figures & data

Table 1 Demographic and Baseline Characteristics of Study Population

Variable Summaries
Number of Patients, n	11
Age
Mean (SD)	71.3 (14.1)
Gender
Female	11 (91.7%)
Male	1 (8.3%)
Ethnicity
Asian	1 (8.3%)
Black	2 (16.7%)
Caucasian	9 (75.0%)
Number of Eyes, n	12
Glaucoma Type
Primary Open Angle Glaucoma	12 (100.0%)
Glaucoma Severity
Severe	12 (100.0%)
Lens Status
Phakic	1 (8.3%)
Pseudophakic	11 (91.7%)
Previous Ocular Procedures
Previous glaucoma procedures	10 (83.3)
MicroPulse cyclophotocoagulation	7 (58.3%)
KDB	1 (8.3%)
XEN45 implant	4 (33.3%)
SLT	2 (16.7%)
Trabeculectomy	1 (8.3%)
CyPass implant	1 (8.3%)
No prior glaucoma procedures	2 (16.7%)
Glaucoma Medications
Mean (SD)	3.0 (0.9)
Intraocular Pressure
Mean (SD)	29.0 (7.6)

Abbreviations: SD, Standard Deviation; KDB, Kahook Dual Blade; SLT, Selective Laser Trabeculoplasty.

Table 2 Mean Intraocular Pressure and Glaucoma Medication Use at Each Study Visit

Visit	Number of Eyes, n	Mean (SD)	Mean Reduction from Baseline (SD)	Mean % Reduction	P-value
Intraocular Pressure, mmHg
Baseline	12	29 (±7.6)
Day 1	12	6.9 (4.0)	−22.1 (6.6)	−76.1%	<0.0001
Week 1	12	5.9 (2.6)	−23.1 (7.2)	−79.6%	<0.0001
Month 1	12	10.8 (2.9)	−18.2 (7.9)	−62.7%	<0.0001
Month 3	9	10.8 (3.0)	−21.0 (5.6)	−62.8%	<0.0001
Month 6	12	11.2 (3.9)	−17.8 (9.1)	−61.5%	<0.0001
Month 12	7	10.0 (3.1)	−15.3 (6.5)	−65.5%	0.0008
Month 18	7	12.3 (4.3)	−18.7 (8.3)	−57.6%	0.001
Month 24	5	11.2 (4.7)	−16.0 (10.8)	−61.4%	0.029
Month 36	9	10.6 (5.5)	−17.1 (9.9)	−61.8%	0.0008
Number of Glaucoma Medications, n
Baseline	12	3.0 (0.9)
Day 1	12	0.3 (0.7)	−2.7 (1.6)	−88.9%	<0.0001
Week 1	12	0.2 (0.6)	−2.8 (1.1)	−91.7%	<0.0001
Month 1	12	0.3 (0.7)	−2.7 (1.2)	−88.9%	<0.0001
Month 3	9	0.9 (0.9)	−2.2 (1.2)	−70.4%	0.0005
Month 6	12	0.7 (0.9)	−2.3 (1.3)	−77.8%	<0.0001
Month 12	7	0.6 (0.8)	−2.3 (1.4)	−81.0%	0.0047
Month 18	7	0.7 (0.9)	−2.0 (1.2)	−76.2%	0.0038
Month 24	5	0.6 (0.5)	−2.6 (0.9)	−80.0%	0.0029
Month 36	9	0.9 (0.9)	−2.2 (1.2)	−71.4%	0.0005

Abbreviation: SD, Standard Deviation.

Figure 1 Mean intraocular pressure at each time point. Error bars represent standard deviation. Reductions from baseline were statistically significant at each time point (P<0.05).

Figure 2 Mean glaucoma medication use at each time point. Error bars represent standard deviation. Reductions from baseline were statistically significant at each time point (P<0.05).

Table 3 The Nature and Frequency of Postoperative Complications

Event	Incidence, n (%)
Hyphema	4 (33.3)
Anterior chamber inflammation	4 (33.3)
Pain	3 (25.0)
Shallow anterior chamber	1 (8.3)

Data Sharing Statement

The author’s institution does not authorize data sharing. Any queries or requests should be directed to the corresponding author (SD).