Keratopathy, cataract, and dry eye in a survey of aniridia subjects

Figures & data

Figure 1 Cumulative percentage of aniridic subjects reporting corneal disease and treatment with corneal surgery.

Figure 2 Cumulative percentage of aniridic subjects reporting cataract and treatment with cataract surgery.

Table 1 Characteristics of subjects

Characteristics	Subjects (N=99)
Age at time of survey
Mean ± SD (years)	25.3±18.6
Range (years)	0–67
Age at time of diagnosis
Mean ± SD (years)	3.3±6.5
Range (years)	0–44
Sex, n (%)
Male	35 (35.4)
Female	64 (64.6)
Race, n (%)
Caucasian	87 (87.9)
African-American	3 (3.0)
Asian	7 (7.1)
Hispanic	4 (4.0)
Heredity, n (%)
Familial	34 (34.3)
Sporadic	57 (57.6)
Unsure	8 (8.1)

Abbreviation: SD, standard deviation.

Table 2 Keratopathy and cataract in aniridic subjects

	Keratopathy (N=99)	Cataract (N=99)
Diagnosis, n (%)
Yes	45 (45.5)	64 (64.6)
No	32 (32.3)	28 (28.3)
Unsure	22 (22.2)	7 (7.1)
Age at diagnosis
Mean ± SD (years)	20.0±12.2	9.4±14.0
Range (years)	0–53	0–50
Surgery
N (%)	20 (20.2)a	32 (32.3)
Age at surgery, mean ± SD (years)	33.5±11.4	28.4±13.7
Age at surgery, range (years)	20–54	4.5–51

Note:

a Keratolimbal allograft was reported in 20 subjects, with additional penetrating keratoplasty in nine of these 20 subjects.

Abbreviation: SD, standard deviation.