Correlation between optic nerve involvement and chronic obstructive pulmonary disease

Figures & data

Figure 1 Visual evoked potential of a healthy participant.

Notes: Normal visual evoked potential waveform parameters on both sides. (A) Visual evoked potential of the right eye. (B) Visual evoked potential of the left eye. (C) Parameters of both eyes.
Abbreviations: Ampl, amplitude; Div, division; Fz, lead placed at the mid line frontal; Lat, latency; Oz, lead placed at the mid line occipital; rec, recording; Stim, stimulating.

Figure 2 Visual evoked potential of a patient with COPD.

Notes: Left side P100 latency was prolonged; Conclusion: normal right side visual evoked potential waveform parameters and mild demyelinating type lesion on left side optic pathway. (A) Visual evoked potential of the right eye. (B) Visual evoked potential of the left eye. (C) Parameters of both eyes.
Abbreviations: Ampl, amplitude; COPD, chronic obstructive pulmonary disease; Div, division; Fz, lead placed at the mid line frontal; Lat, latency; Oz, lead placed at the mid line occipital; rec, recording; Stim, stimulating.

Table 1 Results of VEP studies in two groups

VEP	COPD	Control	P-value
Right P100 latency, ms	118.2±11.9	110.2±4.4	0.001
Left P100 latency, ms	119.7±12.4	110.6±4.9	0.001
Right P100/N140 amplitude, mV	10.9±5.0	9.3±5.8	–
Left P100/N140 amplitude, mV	9.5±4.1	8.5±4.8	–

Abbreviations: COPD, chronic obstructive pulmonary disease; VEP, visual evoked potential.