Optomap ultrawide field imaging identifies additional retinal abnormalities in patients with diabetic retinopathy

Figures & data

Figure 1 Example Optomap UWFSLO image of a patient with DR with ETDRS seven-field mask overlaid.

Abbreviations: UWFSLO, ultrawide field scanning laser ophthalmoscope; DR, diabetic retinopathy; ETDRS, Early Treatment Diabetic Retinopathy Study.

Table 1 Cross-tabulation of DR severity grading derived from ETDRS seven-field images and UWFSLO images

DR grades using ETDRS seven-field view (ICDR severity scale)	DR grades using Optomap UWFSLO view (ICDR severity scale)							Total (%)
	Very mild NPDR (20)	Mild NPDR (35)	Moderate NPDR (43, 47)	Severe NPDR (53 A to D)	Very severe NPDR (53 E)	Mild PDR (61)	Moderate PDR (65)
Very mild NPDR (20)	16	18	0	0	0	0	0	34 (12.8)
Mild NPDR (35)	0	139	18	0	0	0	0	157 (59)
Moderate NPDR (43, 47)	0	0	57	4	0	0	0	61 (23)
Severe NPDR (53 A to D)	0	0	0	11	0	0	0	11 (4)
Very severe NPDR (53 E)	0	0	0	0	0	0	0	0 (0)
Mild PDR (61)	0	0	0	0	0	2	0	2 (0.8)
Moderate PDR (65)	0	0	0	0	0	0	1	1 (0.4)
Total (%)	16 (6)	157 (59)	75 (28.2)	15 (5.6)	0 (0)	2 (0.8)	1 (0.4)	266

Notes: Unweighted κ=0.74±0.04 (95% CI: 0.67–0.81), weighted κ=0.80±0.03 (95% CI: 0.74–0.86).

Abbreviations: CI, confidence interval; DR, diabetic retinopathy; UWFSLO, ultrawide field scanning laser ophthalmoscope; ETDRS, Early Treatment Diabetic Retinopathy Study; ICDR, International Clinical Diabetic Retinopathy; NPDR, nonproliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy.

Figure 2 Optomap UWFSLO image showing a retina with predominantly peripheral lesions outside the ETDRS seven-field view.

Notes: The area within the white rectangle has been magnified to show a large cluster of deep hemorrhages.
Abbreviations: UWFSLO, ultrawide field scanning laser ophthalmoscope; ETDRS, Early Treatment Diabetic Retinopathy Study.