Outcomes of Ahmed glaucoma valve implantation in advanced primary congenital glaucoma with previous surgical failure

Figures & data

Table 1 Preoperative clinical features of the recruited patients

Case no	Sex	Age (year)	Eye	Times of previous surgeries	Previous surgical procedures	BCVA	IOP (mmHg)	Axial length (mm)	HCD (mm)	C/D
1	M	6.5	L	1	Trabeculectomy	0.02	55	27.56	13	1.0
2	F	5.4	L	3	Trabeculotomy	0.05	40	27.63	15	0.95
					Trabeculectomy
					Trabeculectomy + MMC
3	M	1.1	R	1	Trabeculotomy + Trabeculectomy	FO	40	30.80	16	*
4	M	5.7	L	2	Trabeculotomy	0.1	35	25.56	14	0.9
					Trabeculectomy + MMC
5	M	3	R	2	Trabeculotomy	0.06	38	28.40	15.5	0.9
					Trabeculectomy
6	F	3.5	L	1	Trabeculotomy + Trabeculectomy	FC	36	29.32	15	1.0
		3.6	R	1	Trabeculotomy + Trabeculectomy	FC	39	29.26	15.5	1.0
7	M	5.8	R	2	Trabeculotomy + Trabeculectomy	FC	40	26.37	15.5	0.95
					Trabeculectomy + MMC
			L	1	Trabeculotomy + Trabeculectomy	0.01	35	26.11	15	0.95
8	M	3.4	L	1	Trabeculotomy + Trabeculectomy	HM	38	29.21	16	*
9	F	6.2	R	1	Trabeculectomy	0.1	40	26.47	13	0.95
			L	1	Trabeculectomy	0.2	45	26.16	13	0.9
10	F	1.2	R	1	Trabeculotomy + Trabeculectomy	FO	30	27.53	14.5	*
11	M	2.7	L	1	Trabeculotomy + Trabeculectomy	FF	42	27.60	15	1.0

Note:

* Couldn’t be seen because of corneal opacity.

Abbreviations: BCVA, best-corrected visual acuity; IOP, intraocular pressure; HCD, horizontal corneal diameter; F, female; M, male; L, left; R, right; MMC, mitomycin C; C/D, cup to disc; FO, follow object; FC, finger count; HM, hand motion; FF, fixate and follow.

Figure 1 The mean intraocular pressures (IOPs) before operation and during the follow-up period.

Notes: The mean IOPs before the operation and during the follow-up period revealed that the postoperative IOPs were significantly lower than preoperative IOPs at all time points (P<0.001). Error bar: 1.96 standard deviations.
Abbreviations: wk, week; mo, month.

Figure 2 The mean number of glaucoma medications before operation and during the follow-up period.

Notes: The mean number of glaucoma medications before operation and during the follow-up period revealed that the patients needed less glaucoma medications after operation (P<0.001). Error bar: 1.96 standard deviations.
Abbreviations: wk, week; mo, month.

Table 2 Outcome of AGV implant in the recruited patients

Case no	Eye	Follow-up time (months)	BCVA at last visit	End result	Time of fail (months)
1	L	36	0.02	IOP 26 mmHg with three medications	36
2	L	53	0.08	IOP 20 mmHg with three medications	/
3	R	31	FO	Spontaneous delayed suprachoroidal hemorrahge	31
4	L	31	0.1	IOP 17 mmHg with one medication	/
5	R	9	0.05	Erosion of tube after trauma, removal of the tube, transscleral laser cyclophotoablation	9
6	L	29	FC	Corneal attachment of the tube, IOP 11 mmHg without medications	/
	R	6	LP	Retinal detachment, choroidal detachment	6
7	R	5	FC	Endophthalmitis, erosion of tube, removal of the tube	5
	L	27	0.01	IOP 14 mmHg without medications	/
8	L	7	NLP	Delayed suprachoroidal hemorrahge after trauma	7
9	R	27	0.08	IOP 19 mmHg with two medications	/
	L	27	0.2	IOP 16 mmHg without medications	/
10	R	25	FO	IOP 16 mmHg without medications	/
11	L	24	FF	IOP 16 mmHg with one medication	/

Note: / = success during the follow up period.

Abbreviations: AGV, Ahmed glaucoma valve; BCVA, best-corrected visual acuity; L, left; R, right; IOP, Intraocular pressure; FO, Follow object; FC, finger count; LP, light perception; NLP, no light perception; FF, fixate and follow.

Figure 3 Kaplan–Meier survival analyses showed that the success rates were 85.7%, 71.4%, and 71.4% at 6, 12, and 18 months, respectively.