Incidence of retinal detachment associated with atopic dermatitis in Japan: review of cases from 1992 to 2011

Figures & data

Figure 1 Annual changes in the number of surgically treated retinal detachments, and atopic dermatitis patients.

Notes: (A) Number of retinal detachments with atopic dermatitis each year. (B) Number of total retinal detachments each year. (C) Annual changes in atopic dermatitis patients. The number of new atopic dermatitis outpatients seen in the Department of Dermatology, Mie University, Graduate school of Medicine each year. Data for the year 1998 were not available.

Table 1 Preoperative characteristics of 1,643 eyes

	AD group	Non-AD group	P-value
Total number	101 eyes, 87 patients	1,542 eyes, 1,446 patients
Unilateral:Bilateral (patient)	73:14	1,350:96	0.0011
Male:Female (patient)	56:31	860:586	0.4287
Side, Right:Left (eye)	59:42	851:691	0.5968
Age, year, range (mean)	12–57 (22.9)	6–91 (51.3)	<0.0001
Retinal or ciliary break
&emspPars plicata	30 (17.9%)	2 (0.1%)
&emspPars plana	29 (17.4%)	17 (0.7%)
&emspOra	49 (29.3%)	81 (3.2%)
&emspTear	32 (19.2%)	1,360 (53.4%)
&emspHole	27 (16.2%)	956 (37.5%)
&emspMacular hole	0 (0%)	131 (5.1%)	<0.0001
Macular, Off:On (eye)	37:64	786:756	0.0052
CD (+):CD (−) (eye)	85:16	76:1,466	<0.0001

Abbreviations: AD, atopic dermatitis; CD, detachment of ciliary epithelium.

Table 2 Visual acuity before and after surgery: the comparison between AD and non-AD groups

	Preoperative visual acuity			Postoperative visual acuity
	AD group (%)	Non-AD group (%)	P-value	AD group (%)	Non-AD group (%)	P-value
20/15 to 20/25	39 (39.8%)	555 (37.4%)		62 (63.3%)	703 (47.4%)
20/30 to 20/50	21 (21.4%)	224 (15.1%)		20 (20.4%)	337 (22.7%)
20/60 to 20/200	18 (18.4%)	226 (15.3%)		12 (12.2%)	294 (19.8%)
Less than 20/200	20 (20.4%)	478 (32.2%)	0.1498	4 (4.1%)	149 (10.1%)	0.0002

Abbreviation: AD, atopic dermatitis.

Table 3 Preoperative characteristics of 101 eyes

	Former AD group	Recent AD group	P-value
Total number	63 eyes, 49 patients	38 eyes, 38 patients
Unilateral:Bilateral (patient)	35:14	38:0	0.0002
Male:Female (patient)	28:21	28:10	0.1692
Side, Right:Left (eye)	37:26	22:16	0.9342
Age, year, range (mean)	12–41 (21.2)	12–57 (25.6)	0.0084
Retinal or ciliary break
&emspPars plicata	22 (21.0%)	8 (13.3%)
&emspPars plana	19 (18.1%)	10 (16.7%)
&emspOra	34 (32.4%)	15 (25.0%)
&emspTear	18 (17.1%)	14 (23.3%)
&emspHole	12 (11.4%)	13 (21.7%)	0.2523
Lens status
&emspCataract (−)	15 (23.8%)	7 (18.4%)
&emspCataract (+)	33 (52.4%)	18 (47.4%)
&emspAphakia	10 (15.9%)	4 (10.5%)
&emspPseudophakia	5 (7.9%)	9 (23.7%)	0.1602
Macular, Off:On (eye)	24:39	13:25	0.7885
CD (+):CD (−) (eye)	53:10	32:6	0.9911
RD with AD:Total RD (eye)	63:796	38:847	0.0038

Abbreviations: AD, atopic dermatitis; CD, detachment of ciliary epithelium; RD, retinal detachment.

Table 4 Visual acuity before and after surgery: the comparison between former and recent AD groups

	Preoperative visual acuity			Postoperative visual acuity
	Former AD group (%)	Recent AD group (%)	P-value	Former AD group (%)	Recent AD group (%)	P-value
20/15 to 20/25	22 (36.1%)	17 (46.0%)		40 (65.6%)	22 (59.5%)
20/30 to 20/50	13 (21.3%)	8 (21.6%)		10 (16.4%)	10 (27.0%)
20/60 to 20/20	10 (16.4%)	8 (21.6%)		7 (11.5%)	5 (13.5%)
Less than 20/200	16 (26.2%)	4 (10.8%)	0.1952	4 (6.5%)	0 (0.0%)	0.8386

Abbreviation: AD, atopic dermatitis.