Clinical and imaging characteristics of orbital metastatic lesions among Egyptian patients

Figures & data

Table 1 Types of primary tumors and patients’ demographic data

Primary tumor	Patients, n (%)	Males, n	Females, n	Mean age, years	Known cancer patients, n (%)
Breast carcinoma	8 (21.6)	0	8	51.6	7 (87.5)
Hepatocellular carcinoma	6 (16.2)	6	0	60.2	3 (50.0)
Malignant melanoma	5 (13.5)	2	3	44.2	3 (60.0)
Bronchogenic carcinoma	3 (8.1)	2	1	53.7	2 (66.7)
Prostatic carcinoma	3 (8.1)	3	0	67.7	2 (66.7)
Thyroid adenocarcinoma	3 (8.1)	1	2	59.3	2 (66.7)
Renal cell carcinoma	2 (5.4)	2	0	55.5	2 (100.0)
Neuroblastoma	3 (8.1)	2	1	1.5	3 (100.0)
Leukemia	2 (5.4)	0	2	10.5	2 (100.0)
Ewing sarcoma	2 (5.4)	2	0	3.5	2 (100.0)

Table 2 Clinical and imaging characteristics of orbital metastatic lesions

Presenting symptom/sign	Patients, n (%)	Form of lesion in CT and/or MRI	Patients, n (%)
Proptosis and/or globe displacement	29 (78.4)	Infiltrative lesion	23 (62.2)
Diplopia and/or limited ocular motility	13 (35.1)	Mass	8 (21.6)
Pain	6 (16.2)	Isolated muscle thickening	4 (10.8)
Inflammatory manifestations	4 (10.8)	Bone metastasis	2 (5.4)
Ptosis	2 (5.4)
Enophthalmos	1 (2.7)

Abbreviations: CT, computed tomography; MRI, magnetic resonance imaging.

Figure 1 Imaging patterns of orbital metastasis.

Notes: (A) Magnetic resonance image showing right infiltrative metastatic lesion from breast carcinoma (arrow). (B) Computed tomography (CT) scan with contrast showing well-defined right superior orbital metastatic mass from thyroid carcinoma (arrow). (C) CT scan with contrast showing right isolated medial rectus thickening in a case of orbital metastasis from cutaneous malignant melanoma (arrow).

Figure 2 Computed tomography scans with contrast showing bone changes in orbital metastasis.

Notes: (A) Osteoclastic metastatic lesion from hepatocellular carcinoma (arrow). (B) Osteoblastic metastatic lesion from prostatic carcinoma (arrow).