Figures & data
Table 1 Patient characteristics
Figure 1 Fibronectin 1 is overexpressed in metastatic PTC.
Abbreviations: PTC, papillary thyroid cancer; qRT-PCR, quantitative reverse-transcription polymerase chain reaction; mRNA, messenger RNA.
![Figure 1 Fibronectin 1 is overexpressed in metastatic PTC.](/cms/asset/177b35e5-e9a0-4505-80ee-df5976273112/dott_a_12195391_f0001_c.jpg)
Table 2 Fibronectin 1 evaluation and pathological results for metastatic cervical lymph nodes
Table 3 Correlations between fibronectin 1 expression and clinicopathological characteristics in PTC
Table 4 Univariate and multivariate regression analysis of parameters associated with LNM
Figure 2 Potential diagnostic value of fibronectin 1.
Abbreviations: ROC, receiver-operating characteristic; AUC, area under the curve.
![Figure 2 Potential diagnostic value of fibronectin 1.](/cms/asset/3413dfd6-5e14-47c4-b930-a7d2fb252c53/dott_a_12195391_f0002_c.jpg)
Table 5 Performance of fibronectin 1 in differentiating LNM in PTC
Figure 3 Fibronectin 1 knockdown suppresses K1 proliferation.
Abbreviations: qRT-PCR, quantitative reverse-transcription polymerase chain reaction; mRNA, messenger RNA; shRNA, short hairpin RNA; Scr-shRNA, scrambled shRNA.
![Figure 3 Fibronectin 1 knockdown suppresses K1 proliferation.](/cms/asset/678ac75c-b891-4b1e-9b29-9d01618d9fce/dott_a_12195391_f0003_c.jpg)
Figure 4 Fibronectin 1 knockdown inhibits the migration and invasion of K1.
Abbreviations: shRNA, short hairpin RNA; Scr-shRNA, scrambled shRNA.
![Figure 4 Fibronectin 1 knockdown inhibits the migration and invasion of K1.](/cms/asset/b562039b-1a8f-4bed-916b-695b1aa7062f/dott_a_12195391_f0004_c.jpg)
![Figure 4 Fibronectin 1 knockdown inhibits the migration and invasion of K1.](/cms/asset/e9b7da5a-376c-4a57-a0e1-e04017ad5719/dott_a_12195391_f0004a_c.jpg)
Figure 5 Fibronectin 1 overexpression promotes TPC1 proliferation.
Abbreviations: qRT-PCR, quantitative reverse-transcription polymerase chain reaction; mRNA, messenger RNA.
![Figure 5 Fibronectin 1 overexpression promotes TPC1 proliferation.](/cms/asset/dc486b33-eaa4-4d82-962f-6de7d8f52c68/dott_a_12195391_f0005_c.jpg)
Figure 6 Fibronectin 1 overexpression promotes the migration and invasion of TPC1.
![Figure 6 Fibronectin 1 overexpression promotes the migration and invasion of TPC1.](/cms/asset/f4fbb6ab-a10f-403d-b0f6-f17a1b1efdfe/dott_a_12195391_f0006_c.jpg)