Figures & data
Table 1 The primers used for real-time PCR
Figure 1 Isoorientin inhibits cell proliferation.
![Figure 1 Isoorientin inhibits cell proliferation.](/cms/asset/7594156f-e5f9-4623-a492-7bab65fd3202/dott_a_122653_f0001_c.jpg)
Figure 2 AMPK is constitutively activated by isoorientin.
Abbreviations: AMPK, AMP-activated protein kinase; PC, pancreatic cancer.
![Figure 2 AMPK is constitutively activated by isoorientin.](/cms/asset/7a86551d-a3ab-4695-bdda-b40b6274dbbe/dott_a_122653_f0002_c.jpg)
Figure 3 Pancreatic cancer cells are susceptible to isoorientin-induced apoptosis.
![Figure 3 Pancreatic cancer cells are susceptible to isoorientin-induced apoptosis.](/cms/asset/552fbca3-ca40-4345-ab57-5afb39821b91/dott_a_122653_f0003_c.jpg)
Figure 4 Isoorientin downregulates the expression of VEGF, MMPs, and proteins involved in the epithelial–mesenchymal transition.
Abbreviation: ELISA, enzyme-linked immunosorbent assay; MMP, matrix metalloproteinases; qRT-PCR, quantitative real-time PCR; VEGF, vascular endothelial growth factor.
![Figure 4 Isoorientin downregulates the expression of VEGF, MMPs, and proteins involved in the epithelial–mesenchymal transition.](/cms/asset/8497d7f2-0568-4cad-a80b-3916075643e2/dott_a_122653_f0004_c.jpg)
![Figure 4 Isoorientin downregulates the expression of VEGF, MMPs, and proteins involved in the epithelial–mesenchymal transition.](/cms/asset/bd9c74db-0516-4dd5-a716-9387d976c8d1/dott_a_122653_f0004a_c.jpg)
Figure 5 Isoorientin inhibits the migration and invasion of pancreatic cancer cells.
![Figure 5 Isoorientin inhibits the migration and invasion of pancreatic cancer cells.](/cms/asset/61fbfe00-3c22-4c24-aa02-c1e8d16968f8/dott_a_122653_f0005_c.jpg)
![Figure 5 Isoorientin inhibits the migration and invasion of pancreatic cancer cells.](/cms/asset/c068e63d-5d4f-4654-9465-57e191c2356d/dott_a_122653_f0005a_c.jpg)