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Original Research

Overall survival in renal cell carcinoma after introduction of targeted therapies: a Norwegian population-based study

, , , , , , , & show all
Pages 371-385 | Published online: 16 Jan 2017

Figures & data

Table 1 Patient baseline and disease characteristics

Table 2 Distribution of subjects with first-line therapy and lines of therapy prescribed by year of mRCC diagnosis in Norwegian patients with mRCC

Figure 1 Kaplan–Meier estimates of OS in Norwegian patients diagnosed with RCC: (A) by year of diagnosis and (B) by cohorts 2002–2005, 2006–2008, and 2009–2011.

Abbreviations: mo, months; NR, not reached; OS, overall survival; RCC, renal cell carcinoma.
Figure 1 Kaplan–Meier estimates of OS in Norwegian patients diagnosed with RCC: (A) by year of diagnosis and (B) by cohorts 2002–2005, 2006–2008, and 2009–2011.

Figure 2 Kaplan–Meier estimates of OS in Norwegian patients diagnosed with mRCC: (A) by year of diagnosis and (B) by cohorts 2002–2005, 2006–2008, and 2009–2011.

Abbreviations: mo, months; mRCC, metastatic renal cell carcinoma; OS, overall survival.
Figure 2 Kaplan–Meier estimates of OS in Norwegian patients diagnosed with mRCC: (A) by year of diagnosis and (B) by cohorts 2002–2005, 2006–2008, and 2009–2011.

Figure 3 Kaplan–Meier estimates of OS in Norwegian patients diagnosed with mRCC of different histology.

Abbreviations: mo, months; mRCC, metastatic renal cell carcinoma; OS, overall survival.
Figure 3 Kaplan–Meier estimates of OS in Norwegian patients diagnosed with mRCC of different histology.

Table 3 Multivariate Cox proportional hazards regression analysis for factors predictive for OS in RCC, mRCC, and subgroups of mRCC patients in Norway diagnosed between 2002 and 2011

Figure 4 Kaplan–Meier estimates of OS adjusted by multivariate Cox proportional hazards regression analysis in Norwegian patients diagnosed with: (A) mRCC, by TT; (B) primary mRCC, by CN only, TT only, both CN and TT, and neither treatment; and (C) mRCC, who were aged 75 years or older, by TT.

Abbreviations: CN, cytoreductive nephrectomy; HR, hazard ratio; mo, months; mRCC, metastatic renal cell carcinoma; OS, overall survival; TT, targeted therapy.
Figure 4 Kaplan–Meier estimates of OS adjusted by multivariate Cox proportional hazards regression analysis in Norwegian patients diagnosed with: (A) mRCC, by TT; (B) primary mRCC, by CN only, TT only, both CN and TT, and neither treatment; and (C) mRCC, who were aged 75 years or older, by TT.

Figure S1 Kaplan–Meier estimates of OS in Norwegian patients diagnosed with primary mRCC by (A) year of diagnosis and (B) cohorts.

Abbreviations: mo, months; mRCC, metastatic renal cell carcinoma; OS, overall survival.

Figure S1 Kaplan–Meier estimates of OS in Norwegian patients diagnosed with primary mRCC by (A) year of diagnosis and (B) cohorts.Abbreviations: mo, months; mRCC, metastatic renal cell carcinoma; OS, overall survival.

Figure S2 Kaplan–Meier estimates of OS in Norwegian patients diagnosed with mRCC who were aged 75 years or older by (A) year of mRCC diagnosis and (B) cohorts.

Abbreviations: mo, months; mRCC, metastatic renal cell carcinoma; OS, overall survival.

Figure S2 Kaplan–Meier estimates of OS in Norwegian patients diagnosed with mRCC who were aged 75 years or older by (A) year of mRCC diagnosis and (B) cohorts.Abbreviations: mo, months; mRCC, metastatic renal cell carcinoma; OS, overall survival.

Figure S3 Kaplan–Meier estimates of OS in Norwegian patients diagnosed with mRCC by line of therapy.

Abbreviations: mo, months; mRCC, metastatic renal cell carcinoma; OS, overall survival.

Figure S3 Kaplan–Meier estimates of OS in Norwegian patients diagnosed with mRCC by line of therapy.Abbreviations: mo, months; mRCC, metastatic renal cell carcinoma; OS, overall survival.

Table S1 Multivariate Cox proportional hazards regression analysis of factors, including line of therapy, predictive for OS in mRCC patients in Norway diagnosed between 2002 and 2011

Table S2 Multivariate Cox proportional hazards regression analysis by region for OS in RCC and mRCC patients in Norway diagnosed between 2002 and 2011