Parity association with clinicopathological factors in invasive breast cancer: a retrospective analysis

Figures & data

Figure 1 Age distribution of 392 patients at diagnosis of breast cancer.

Note: The age of the patients from Shaoguan ranged from 24 to 80 years and was normal distribution, with the peak age of onset of breast cancer being 48 years.

Figure 2 Mean age at diagnosis of breast cancer according to parity.

Notes: Mean age was marked at midpoint of vertical line. The relationship between parity and age was assessed using one-way analysis of variance with post hoc Dunnett’s T3 test. The mean age at diagnosis increased with increased parity. ^*Compared with parity 0 (P=0.005), parity 1 (P<0.001), and parity 2 (P>0.001). ^▲Compared with parity 1 (P=0.021). There was no significant difference in the mean age of patients with parity 0 and parity 1 (P=0.997) or between patients with parity 0 and parity 2 (P=0.539).

Table 1 Associations between parity and clinicopathological factors in invasive breast cancer

Clinicopathological factors	Parity				Statistical analysis
	0	1	2	3
Age, years (mean ± SD)	45.1±2.4	46.3±0.6	49.2±0.8	55.8±1.3	F=18.117, P<0.001
Tumor size					CC =0.081, P=0.109
≤2 cm	5	74	52	22
2–5 cm	8	87	93	33
>5 cm	2	4	7	5
ALN metastasis					CC =−0.340, P<0.001
0	5	87	67	28
1–3	6	45	39	12
4–9	4	18	21	10
≥10	0	15	25	10
Grade					CC =0.024, P=0.633
I	3	9	10	2
II	8	117	100	45
III	4	39	42	13
Subtype					χ^2=10.184, P=0.336
Luminal A	3	50	37	11
Luminal B	7	66	70	27
HER2	0	21	18	12
TN	5	28	27	10

Abbreviations: ALN, axillary lymph node; CC, correlation coefficient; TN, triple-negative.