Figures & data
Figure 1 Immune response to tumors.
Abbreviations: MHC, major histocompatibility complex; PD-1, programmed cell death-1; PD-L1, programmed death-ligand 1.
![Figure 1 Immune response to tumors.](/cms/asset/cfd66da7-688d-49e0-a7c5-99e5f3716ec3/dott_a_12195405_f0001_c.jpg)
Figure 2 Escaping immune surveillance.
![Figure 2 Escaping immune surveillance.](/cms/asset/b49116cf-1805-4560-9a62-d6b77c85a41a/dott_a_12195405_f0002_c.jpg)
Table 1 Checkpoint inhibitors available in the USA and select inhibitors in advanced studies
Table 2 Review of select biomarker studies and their ability to enrich responding patient populations
Table 3 Ongoing trials of agents targeting the PD-1 or PD-L1 pathway for treatment of pediatric cancer