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Original Research

Tyrosine kinase domain mutations of EGFR gene in head and neck squamous cell carcinoma

, , , , , , , , & show all
Pages 1527-1533 | Published online: 13 Mar 2017

Figures & data

Figure 1 The somatic mutations of EGFR detected by Therascreen® EGFR RGQ PCR kit.

Notes: The schematic representation of all 29 mutations detected by the Therascreen EGFR RGQ PCR kit and the frequency detected in the present study. The mutations are color coded based on the respective exons. All somatic mutations on exon 18 are coded in shades of blue; exon 19 mutations are coded in shades of gray; exon 20 mutations are coded in shades of orange; and exon 21 mutations are coded in shades of green.
Abbreviations: EGFR, epidermal growth factor receptor; RGQ, Rotor-Gene Q; PCR, polymerase chain reaction.
Figure 1 The somatic mutations of EGFR detected by Therascreen® EGFR RGQ PCR kit.

Table 1 Patient characteristics

Table 2 Effect of parameters on EGFR mutation

Table 3 Association of age, gender, smoking status, and prognosis with the individual EGFR mutations