Figures & data
Figure 1 Polymerase chain reaction-direct sequencing.
Notes: Chromatogram showing the germline mutation in the case included in the present study. Arrow indicates the missense variant c.C952T>C (p.C318R) in exon 5 of GATA3.
Figure 2 Pedigree.
Notes: Arrow indicates the proband. Males are represented by squares and females by circles. The filled circle indicates the affected female. A diagonal line through a square or circle indicates a deceased person.
Figure 3 Images of bronchoscopic specimens stained for H&E and the indicated markers.
Notes: Dysplasia with a coarse chromatin was observed in fibrous tissue. The tumor was positive for CK 5/6 and p63, weakly positive for TTF-1, and negative for Napsin. Magnification is ×400.
Abbreviations: CK 5/6, cytokerTIN 5/6; H&E, hematoxylin and eosin; TTF-1, thyroid transcription factor-1.
Abbreviations: CK 5/6, cytokerTIN 5/6; H&E, hematoxylin and eosin; TTF-1, thyroid transcription factor-1.
Figure 4 Age of nonsmoking patients diagnosed with lung squamous cell carcinoma at Kobe University Hospital from 2011 to 2017.
Note: Of 263 patients diagnosed with lung squamous cell carcinoma at Kobe University Hospital, 16 were nonsmokers.
Figure 5 Chest X-ray.
Note: Left pleural effusion, pleural thickening, and scoliosis were detected.
Abbreviations: R, right; P-A, posteroanterior.
Abbreviations: R, right; P-A, posteroanterior.
