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Review

Potential New Cancer Immunotherapy: Anti-CD47-SIRPα Antibodies

, , , , ORCID Icon & ORCID Icon
Pages 9323-9331 | Published online: 22 Sep 2020

Figures & data

Table 1 Targeted CD47/SIRPα Antibody Research in Recent Years

Figure 1 The timeline of the key discoveries.

Figure 1 The timeline of the key discoveries.

Figure 2 (A) CD47-SIRPɑ interaction blocks macrophage phagocytosis of cancer cells. (B) Treatment of cancer cells treated with anti-CD47/SIRPɑ Ab induces phagocytosis by macrophage.

Figure 2 (A) CD47-SIRPɑ interaction blocks macrophage phagocytosis of cancer cells. (B) Treatment of cancer cells treated with anti-CD47/SIRPɑ Ab induces phagocytosis by macrophage.

Figure 3 The value of CD47 in the diagnosis, treatment, and prognosis assessment of various tumors.

Figure 3 The value of CD47 in the diagnosis, treatment, and prognosis assessment of various tumors.