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OncoTargets and Therapy Volume 14, 2021 - Issue
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Case Report

Clinical and Pathologic Complete Response to Gefitinib in a Patient with SqCLC Harboring EGFR p.E746_S752delinsV Mutation

Weitao Zhuang1 Department of Thoracic Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, People’s Republic of China;2 Shantou University Medical College, Shantou, 515041, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-8679-4109
ORCID Icon,
Chao Zhang3 Guangdong Lung Cancer Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, People’s Republic of China
,
Yong Tang1 Department of Thoracic Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0001-9478-5205
ORCID Icon,
Dan Tian1 Department of Thoracic Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, People’s Republic of China
,
Zihua Lan1 Department of Thoracic Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, People’s Republic of China;2 Shantou University Medical College, Shantou, 515041, People’s Republic of China
,
Cheng Zeng1 Department of Thoracic Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, People’s Republic of China
&
Guibin Qiao1 Department of Thoracic Surgery, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, People’s Republic of ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-9200-9317
ORCID Icon show all
Pages 4805-4808 | Published online: 15 Sep 2021

Figures & data

Figure 1 Timeline of the clinical course. Thoracic CT images of the tumor at baseline (A), after neoadjuvant treatment with gefitinib (C and D), and at postoperative follow-up (G and H); Hematoxylin-Eosin stained slide of the core needle biopsy (B), resected primary lesion (E) and resected lymph node (F).

Abbreviations: NSE, neuron-specific enolase; SCC-Ag, squamous cell carcinoma antigen; CYFRA-21-1, cytokeratin 19 fragment; CEA, carcinoembryonic antigen.
Figure 1 Timeline of the clinical course. Thoracic CT images of the tumor at baseline (A), after neoadjuvant treatment with gefitinib (C and D), and at postoperative follow-up (G and H); Hematoxylin-Eosin stained slide of the core needle biopsy (B), resected primary lesion (E) and resected lymph node (F).

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