The clinical significances of the abnormal expressions of Piwil1 and Piwil2 in colonic adenoma and adenocarcinoma

Figures & data

Figure 1 Positive expression of Piwil1 in colon cancer, ×400.

Figure 2 Positive expression of Piwil2 in colon cancer, ×400.

Figure 3 Positive expression of Piwil1 in colonic adenoma, ×400.

Figure 4 Positive expression of Piwil2 in colonic adenoma, ×400.

Figure 5 Negative expression of Piwil1 in para-carcinoma tissue, ×400.

Figure 6 Negative expression of Piwil2 in para-carcinoma tissue, ×400.

Table 1 Positive expression of Piwil1 and Piwil2 proteins in cancer, colonic adenoma, and cancerous tissue

Tissue	Number of cases	Piwil1-positive cases (%)	Piwil2-positive cases (%)
Tissue adjacent to carcinoma	45	5 (11.1)	11 (24.4)
Colonic adenoma	41	22 (53.7)	31 (75.6)
Cancerous tissue	92	74 (80.4)	85 (92.4)

Table 2 Relationship between positive expression of Piwil1 and Piwil2 proteins in colon cancer tissue and its clinicopathological factors

Clinical pathological factors	Number of cases	Number of Piwil1-positive cases (%)	χ^2	P	Number of Piwil2-positive cases (%)	χ^2	P
Sex			1.094	0.296		0.240	0.624
Male	51	43 (84.3)			46 (90.2)
Female	41	31 (75.6)			39 (95.1)
Age (years)			0.112	0.737		1.487	0.223
55 or below	39	32 (82.1)			34 (87.2)
Above 55	53	42 (79.2)			51 (96.2)
AJCC 7th edition			5.403	0.020		1.950	0.163
TNM stage
I + II stage	49	35 (71.4)			43 (91.8)
III + IV stage	43	39 (90.7)			42 (93.0)
Degree of differentiation			10.889	0.001		0.014	0.906
High	31	19 (61.3)			28 (90.3)
Medium or low	61	55 (90.2)			57 (93.4)
Lymph node metastasis			6.546	0.011		0.186	0.666
No	52	37 (71.2)			47 (90.4)
Yes	40	37 (92.5)			38 (95.0)

Abbreviation: AJCC, American Joint Committee on Cancer; TNM, tumour node metastasis.