CYP2C19 polymorphism frequency in Russian patients in Central Russia and Siberia with acute coronary syndrome

Karin B Mirzaev1 Russian Medical Academy of Continuous Professional Education, Ministry of Health of the Russian Federation, MoscowCorrespondence[email protected]

Elena M Zelenskaya2 Federal State-Financed Research Institution “Institute of Chemical Biology and Fundamental Medicine”, Siberian Branch of the Russian Academy of Sciences, Novosibirsk

Olga L Barbarash3 Federal State-Financed Research Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Siberian Branch of the Russian Academy of Sciences, Kemerovo

Vladimir I Ganyukov3 Federal State-Financed Research Institution “Research Institute for Complex Issues of Cardiovascular Diseases”, Siberian Branch of the Russian Academy of Sciences, Kemerovo

Konstantin A Apartsin4 State-Financed Health Institution “Irkutsk Regional Badge of Honour Clinical Hospital”;5 Federal State-Financed Research Institution “Irkutsk Research Center”, Siberian Branch of the Russian Academy of Sciences, Irkutsk City

Natalya O Saraeva4 State-Financed Health Institution “Irkutsk Regional Badge of Honour Clinical Hospital”

Konstantin Y Nikolaev6 Federal State-Financed Research Institution “Research Institute of Internal and Preventive Medicine”;7 Federal State Autonomous Institution of Higher Education “Novosibirsk National Research State University”, Novosibirsk, Russia

Kristina A Ryzhikova1 Russian Medical Academy of Continuous Professional Education, Ministry of Health of the Russian Federation, Moscow

Galina I Lifshits2 Federal State-Financed Research Institution “Institute of Chemical Biology and Fundamental Medicine”, Siberian Branch of the Russian Academy of Sciences, Novosibirsk;5 Federal State-Financed Research Institution “Irkutsk Research Center”, Siberian Branch of the Russian Academy of Sciences, Irkutsk City;7 Federal State Autonomous Institution of Higher Education “Novosibirsk National Research State University”, Novosibirsk, Russia

Dmitry A Sychev1 Russian Medical Academy of Continuous Professional Education, Ministry of Health of the Russian Federation, Moscow

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CYP2C19 polymorphism frequency in Russian patients in Central Russia and Siberia with acute coronary syndrome

Table 1 Allele and genotype frequencies and comparison between Russian acute coronary syndrome patients according to geographical region: Moscow region, Northern, Central, and Eastern Siberia (Fisher’s exact test)

Table 2 CYP2C192, CYP2C193, and CYP2C19*17 frequencies in human populations

Table 3 Frequency distribution of CYP2C192, CYP2C193, and CYP2C1917* allele variants among ethnic groups in Russia

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CYP2C19 polymorphism frequency in Russian patients in Central Russia and Siberia with acute coronary syndrome

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Table 1 Allele and genotype frequencies and comparison between Russian acute coronary syndrome patients according to geographical region: Moscow region, Northern, Central, and Eastern Siberia (Fisher’s exact test)

Table 2 CYP2C19*2, CYP2C19*3, and CYP2C19*17 frequencies in human populations

Table 3 Frequency distribution of CYP2C19*2, CYP2C19*3, and CYP2C19*17 allele variants among ethnic groups in Russia

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Table 2 CYP2C192, CYP2C193, and CYP2C19*17 frequencies in human populations

Table 3 Frequency distribution of CYP2C192, CYP2C193, and CYP2C1917* allele variants among ethnic groups in Russia