Qualitative user evaluation of a revised pharmacogenetic educational toolkit

Figures & data

Table 1 Details of revised toolkit components

Component	Format	Content	Use	Snapshot
Test information sheet	Single 8.5 × 11 inch paper, black and white print, double sided; modeled after Vaccination Information Statements	General overview of PGx testing: Purpose of PGx testing What is involved in testing Risks and benefits of testing	For patients to take home and reference
Flipbook	8.5 × 11 inch 16-page spiral bound book, color print; modeled after flipbooks were used by genetic counselors	Graphics of PGx concepts: • Outcomes when prescribing with PGx information compared to prescribing without • Impact of metabolizer types Text details about medications eligible for testing: • Associated gene • Possible test results • Impact of results on care	For providers to reference in the clinic/pharmacy when discussing PGx testing or testing results
Summary results report	Single 8.5 × 11 inch paper, black and white print	Patient results, interpretation of the result, and guidance for follow-up	For patients to take home and share with other providers
Results card	Wallet-sized card (~3.5 × 2 inches)	PGx genes tested, results (*allele/genotype and phenotype)	For patients to carry with them and share with other providers

Abbreviation: PGx, pharmacogenetics.

Table 2 Qualitative interview guide

Pharmacist interview	Patient interview
For each of the four components:
Format • What is your overall impression of the format? • What format might be better? • What other types of graphics/picture may be helpful to include? • What do you think is the purpose of the component? (Explain the purpose if unclear) How can the format be improved to make it easier to understand the purpose Content/information • What information in the toolkit component is understandable/not understandable? • Do the TIS (#1) and flipbook (#2) make it understandable on how PGx testing will be used? • Is there anything that does not make sense? • Any words you do not understand or that you do not think patients would understand? • Imagine you were considering ordering testing for your patient or having testing yourself – what else would they/you want to know?	Format • What is your overall impression of the format? • What format might be better? • What other types of graphics/picture may be helpful to include? • What do you think is the purpose of the component? (Explain the purpose if unclear) How can the format be improved to make it easier to understand the purpose Content/information • What information in the toolkit component is understandable/not understandable? • Do the TIS and flipbook make it understandable on how PGx testing will be used? • Are there any sentences/sections that do not make sense to you? • Are there any words that you do not understand? Or that you do not think other people (like your family or friends) would understand? • Imagine that you were considering having testing – what else would you want to know?
After reviewing all the four components
Utility • Would you feel better able/more confident/comfortable describing PGx testing to your patients with the toolkit? • Would you use components #1 or #2 of the toolkit with a patient who was considering having PGx testing? Why/why not? • Would you use components #3 or #4 to report results for PGx testing? Why/why not? • What changes would make it more usable? • What other educational tools or information would be useful? • What other formats would you prefer? • What other resources would you use or refer your patient to for more information on PGx? Value What is the primary value/benefit of this toolkit for pharmacists and your patients?	Utility • How is your understanding of PGx testing after reviewing the toolkit? Better/worse? • Which components are most helpful? Which would like to receive/view if you had testing? • Would you recommend components #1 and #2 to someone who is considering to undergo PGx testing? Why/why not? • Would you want your pharmacist to give you components #3 or #4 after receiving results? Why/why not? • What other tools/information would be useful? • What other formats would you prefer? • What additional questions would you have for your pharmacist? • Where would you go to learn more about PGx?

Abbreviations: PGx, pharmacogenetics; TIS, test information sheet; component #1, test information sheet; component #2, flipbook; component #3, summary results report; component #4, results card.