Italian Real-Life Experience of Patients with Hereditary Transthyretin Amyloidosis Treated with Patisiran

Figures & data

Table 1 Outcome Measures Changes Between Baseline and Last Follow-Up

	Baseline	Last Follow-Up
Weight	62	73
PND score	3b	2
FAP stage	2	1
NIS	61	25
6MWT	0	282
Diarrhoea	+++	+
Orthostatic hypotension	+++	/

Notes: +: mild; ++: moderate; +++: severe; /: absent.

Abbreviations: 6MWT, 6-min walking test; FAP, familial amyloid polyneuropathy; NIS, Neuropathy Impairment Score; PND, polyneuropathy disability.

Figure 1 Continued.

Figure 1 (A) Increased echogenicity of the thickened intraventricular septum, with a speckled appearance (B). The strain of the basal walls is severely reduced in comparison to the apical strain, preserved (C). Improvement in the systolic longitudinal function at follow-up.

Figure 2 Anterior projection of planar whole-body bone scan, showing an intense cardiac uptake with reduced bone uptake.