Vitamin D deficiency and anemia risk in children: a review of emerging evidence

Figures & data

Table 1 Overview of studies on relationship between vitamin D deficiency and anemia

Study	Design	Sample size	Age range	Anemia/vitamin D-deficiency risk, OR (95% CI)
Atkinson et al,^Citation16 USA	Cross-sectional	10,410	1–12 years	1.47 (1.14–1.89)*,#
Sim et al,^Citation12 USA	Cross-sectional	554	17–65 years	1.9 (1.3–2.7)**,#
Yoo and Cho,^Citation94 South Korea	Case–control	500	19–91 years	3.32 (2.26–4.85)‡
Coutard et al,^Citation20 France	Case–control	186	70–85 years	1.37 (0.72–2.6)***,‡
Jin et al,^Citation57 South Korea	Case–control	102	3–24 months	4.93 (1.87–12.98)‡
Chang et al,^Citation93 China	Cross-sectional	1,218	6 months–14 years	1.01 (1–1.02)ξ,‡
Golbahar et al,^Citation92 Bahrain	Cross-sectional	421	18–60 years	3.21 (2.13–4.86)

Notes:

* Fully adjusted for age, sex, race, obesity, C-reactive protein, vitamin B₁₂, and folate;

** adjusted for age, sex, and chronic kidney disease;

*** adjusted for albuminemia;

ξ blood lead level as predictor;

# anemia risk;

‡ vitamin D-deficiency risk.

Abbreviations: OR, odds ratio; CI, confidence interval.

AtkinsonMAMelamedMLKumarJVitamin D, race, and risk for anemia in childrenJ Pediatr201416415315824112861

 PubMed Web of Science ®Google Scholar

SimJJLacPTLiuIAVitamin D deficiency and anemia: a cross-sectional studyAnn Hematol20108944745219841921

 PubMed Web of Science ®Google Scholar

YooEHChoHJPrevalence of 25-hydroxyvitamin D deficiency in Korean patients with anemiaJ Clin Lab Anal20152912913424797104

 PubMed Web of Science ®Google Scholar

CoutardAGarlantézecREstivinSAndroMGentricAAssociation of vitamin D deficiency and anemia in a hospitalized geriatric population: denutrition as a confounding factorAnn Hematol20139261561923242475

 PubMed Web of Science ®Google Scholar

JinHJLeeJHKimMKThe prevalence of vitamin D deficiency in iron-deficient and normal children under the age of 24 monthsBlood Res201348404523589794

 PubMedGoogle Scholar

ChangLLiuXShiHDaiWWangHJiangYAssociation of 25-hydroxyvitamin D with Hb and lead in children: a Chinese population-based studyPublic Health Nutr20131782783223890590

 PubMed Web of Science ®Google Scholar

GolbaharJAltayabDCarreonEDarwishAAssociation of vitamin D deficiency and hyperparathyroidism with anemia: a cross-sectional studyJ Blood Med2013412312824039460

 PubMedGoogle Scholar