Recent Application of DNA Microarray Techniques to Diagnose Infectious Disease

Figures & data

Table 1 Recent Applications of DNA Microarray in Microbial Pathogens

Type of DNA Microarray	Pathogen		Target Gene	References
Paper DNA VFM with RPA	N. meningitidis		ctrA gene	[19]
Spotted microarray	Polymicrobial that cause pneumonia		16s rRNA and specific genes for each pathogen	[20]
Magnetic nanoparticles enhanced DNA microarray	Food borne Pathogens	E. coli	rfbE	[21]
		S. enterica	envA
		C. jejuni	ceuE
		V. cholerae	ompW
In situ synthesized chip	Food borne Pathogens	S. typhimurium	invA	[22]
		S. aureus	sasH
		E. coli O157:H7	wzy
		L. monocytogenes	hlyA
		V. parahemolyticus	comEC/ rec2
Covidarray	SARS CoV-2		Nucleocapsid(N1&N2)	[23]
SMAvirusChip	Arboviruses		Structural and non-structural proteins	[24]

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Liu H, Dong H, Chen Z, et al. Magnetic nanoparticles enhanced microarray detection of multiple foodborne pathogens. Biomed Nanotechnol. 2017;13(10):1333–1343. doi:10.1166/jbn.2017.2418

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Hu S, Hu W, Feng K, et al. An in situ-synthesized gene chip for the detection of food-borne pathogens on fresh-cut cantaloupe and lettuce. Front Microbiol. 2020;10:3089. doi:10.3389/fmicb.2019.03089

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Damin F, Galbiati S, Gagliardi S, et al. CovidArray: a microarray-based assay with high sensitivity for the detection of SARS-CoV-2 in nasopharyngeal swabs. Sensors. 2021;21(7):2490. doi:10.3390/s21072490

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Khan MJ, Trabuco AC, Alfonso HL, et al. DNA microarray platform for detection and surveillance of viruses transmitted by small mammals and arthropods. PLoS Negl Trop Dis. 2016;10(9):e0005017. doi:10.1371/journal.pntd.0005017

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