Nonadherence to antihypertensive medications and associated factors in general medicine clinics

Figures & data

Table 1 Baseline characteristics of the study population and estimated ORs between the nonadherence and adherence group in relation to possible explanatory variables using logistic regression analysis

Variables	Total study population: N=302 (%)	Nonadherence: n=37 (%)	Adherence: n=265	OR	95% CI	P-value
Sex
M	112 (37)	16 (14)	96	1.34	0.67–2.7	0.40
F	190 (63)	21 (11)	169
Age, years
≤65	159 (53)	27 (17)	132	2.04	0.98–4.22	0.025
>65	143 (47)	14 (9)	129
Complex therapy
Yes	171 (57)	17 (10)	154	0.61	0.30–1.22	0.16
No	131 (43)	20 (15)	111
Side effects
Yes	114 (38)	14 (12)	100	1.00	0.49–2.04	0.99
No	179 (62)	23 (13)	156
Poor disease knowledge
Yes	243 (80)	30 (12)	213	1.04	0.43–2.51	0.91
No	59 (20)	7 (11)	52
Comorbid conditions
Yes	287 (95)	35 (12)	252	0.90	0.19–4.17	0.89
No	15 (5)	2 (13)	13
Current smoker
Yes	11 (4)	1 (9)	10	0.71	0.09–5.69	0.74
No	291 (96)	36 (12)	255
Poor monitoring
Yes	200 (66)	30 (15)	170	2.39	1.01–5.66	0.040
No	102 (34)	7 (7)	95
Illiterate patients
Yes	194 (64)	24 (12)	170	1.01	0.50–2.0	0.98
No	106 (36)	13 (12)	93
BP ≥140/90 mmHg
Yes	113 (37)	23 (20)	90	2.86	1.40–5.80	0.003
No	189 (63)	15 (8)	174
IHD
Yes	41 (14)	3 (7)	38	0.53	0.15–1.80	0.30
No	261 (86)	34 (13)	227
CVA
Yes	27 (9)	4 (15)	23	1.27	0.41–3.91	0.67
No	257 (91)	33 (13)	242
CRF
Yes	39 (13)	5 (13)	34	1.06	0.38–2.91	0.90
No	263 (87)	32 (12)	231
CHF
Yes	35 (12)	3 (9)	32	0.64	0.18–2.21	0.48
No	265 (88)	34 (13)	233
High cholesterol
Yes	251 (83)	33 (13)	218	1.78	0.60–5.26	0.30
No	51 (17)	4 (15)	47
Diabetes
Yes	222 (73)	28 (13)	194	1.13	0.51–2.53	0.75
No	80 (27)	9 (11)	71

Abbreviations: BP, blood pressure; CHF, congestive heart failure; CI, confidence interval; CRF, chronic renal failure; CVA, cerebral vascular accident; F, female; IHD, ischemic heart disease; M, male; OR, odds ratio.