Estimation of health state utilities in breast cancer

Figures & data

Table 1 Characteristics of participants (n=509)

Characteristics	n	%
Sex
Male	249	48.9
Female	260	51.1
Age group (years)
19–29	91	17.9
30–39	91	17.9
40–49	110	21.6
50–59	101	19.8
≥60	116	22.8
Education level
Middle school or below	44	8.6
High school	239	47.0
College or above	226	44.4
Monthly income (million Korean won)
<3	105	20.6
3–5	253	49.7
>5.0	151	29.7
Ambulatory care visit in the past 2 weeks
Yes	46	9.0
No	463	91.0
Hospitalization in the past 12 months
Yes	11	2.2
No	498	97.8
Morbidity
Yes	46	9.0
No	463	91.0

Table 2 Utility values of breast cancer scenarios derived from the VAS and SG approaches

Health states	n	VAS			SG
		Mean	SD	Median	Mean	SD	Median
1. Noninvasive breast cancer with mastectomy only (AJCC 7th 0)	509	0.669	0.199	0.694	0.790	0.265	0.900
2. Noninvasive breast cancer with mastectomy and followed by reconstruction (AJCC 7th 0)	509	0.681	0.199	0.700	0.804	0.260	0.900
3. Noninvasive breast cancer with breast-conserving surgery and radiation therapy (AJCC 7th 0)	509	0.662	0.201	0.684	0.779	0.261	0.900
4. Invasive breast cancer with surgery (mastectomy or breast-conserving surgery), radiation therapy, and/or chemotherapy (AJCC 7th I, II)	509	0.579	0.202	0.600	0.731	0.255	0.800
5. Locally advanced breast cancer with radical mastectomy and radiation therapy (AJCC 7th IIIA, IIIB)	509	0.435	0.178	0.451	0.610	0.261	0.650
6. Inoperable locally advanced breast cancer (AJCC 7th IIIC)	509	0.415	0.173	0.438	0.587	0.259	0.650
7. Loco-regional recurrent breast cancer	509	0.333	0.176	0.357	0.496	0.260	0.500
8. Metastatic breast cancer (AJCC 7th IV)	509	0.170	0.220	0.167	0.352	0.275	0.300

Abbreviations: VAS, visual analog scale; SG, standard gamble; SD, standard deviation; AJCC, American Joint Committee on Cancer.

Table 3 Utility weights of breast cancer scenarios derived from the SG approach according to sociodemographic factors

Variables	Scenario 1		Scenario 2		Scenario 3		Scenario 4		Scenario 5		Scenario 6		Scenario 7		Scenario 8
	Mean	SD	Mean	SD	Mean	SD	Mean	SD	Mean	SD	Mean	SD	Mean	SD	Mean	SD
Sex
Male	0.786	0.265	0.804	0.259	0.778	0.265	0.735	0.250	0.618	0.258	0.579	0.259	0.502	0.258	0.357	0.277
Female	0.795	0.266	0.803	0.261	0.780	0.258	0.728	0.260	0.603	0.264	0.594	0.259	0.490	0.262	0.347	0.273
Age group (years)
19–29	0.816	0.244	0.824	0.247	0.796	0.253	0.742	0.239	0.599	0.243	0.570	0.240	0.465	0.249	0.325	0.259
30–39	0.746	0.303	0.770	0.291	0.728	0.300	0.714	0.272	0.626	0.260	0.582	0.244	0.488	0.228	0.360	0.250
40–49	0.797	0.267	0.792	0.283	0.787	0.260	0.719	0.269	0.597	0.277	0.556	0.291	0.483	0.280	0.340	0.278
50–59	0.820	0.217	0.824	0.213	0.800	0.224	0.747	0.239	0.614	0.247	0.608	0.239	0.509	0.252	0.374	0.290
≥60	0.773	0.284	0.807	0.258	0.781	0.265	0.735	0.257	0.616	0.275	0.615	0.269	0.525	0.279	0.359	0.292
Education level
High school or below	0.790	0.269	0.799	0.261	0.780	0.260	0.734	0.254	0.598	0.264	0.594	0.259	0.500	0.265	0.341	0.278
College or above	0.791	0.259	0.809	0.259	0.778	0.263	0.728	0.257	0.625	0.257	0.577	0.259	0.490	0.255	0.365	0.271
Monthly income (million Korean won)
<3	0.806	0.263	0.820	0.251	0.806	0.255	0.756	0.256	0.631	0.264	0.603	0.269	0.522	0.283	0.358	0.281
3–5	0.778	0.268	0.791	0.267	0.765	0.263	0.713	0.251	0.590	0.254	0.571	0.248	0.477	0.243	0.339	0.268
>5.0	0.800	0.264	0.814	0.254	0.785	0.262	0.745	0.260	0.629	0.269	0.602	0.270	0.509	0.270	0.370	0.283
Ambulatory care visit in the past 2 weeks
Yes	0.828	0.237	0.851	0.220	0.837	0.232	0.798	0.224	0.685*	0.287	0.668*	0.304	0.614**	0.268	0.417	0.293
No	0.786	0.268	0.799	0.263	0.773	0.263	0.725	0.257	0.603*	0.257	0.579*	0.253	0.484**	0.257	0.345	0.273
Hospitalization in the past 12 months
Yes	0.750	0.259	0.791	0.202	0.759	0.238	0.695	0.258	0.655	0.260	0.641	0.253	0.573	0.263	0.418	0.320
No	0.791	0.266	0.804	0.261	0.780	0.262	0.732	0.255	0.609	0.261	0.586	0.259	0.494	0.260	0.350	0.274
Morbidity
Yes	0.865*	0.199	0.874**	0.175	0.855**	0.192	0.830**	0.173	0.695*	0.255	0.691**	0.237	0.590**	0.256	0.348	0.256
No	0.783*	0.270	0.797**	0.266	0.772**	0.266	0.721**	0.260	0.602*	0.260	0.576**	0.259	0.486**	0.259	0.352	0.277

Notes:

* P-value <0.05;

** P-value <0.01.

Abbreviations: SG, standard gamble; SD, standard deviation.