Self-reported adherence and associated factors to isoniazid preventive therapy for latent tuberculosis among people living with HIV/AIDS at health centers in Gondar town, North West Ethiopia

Figures & data

Table 1 Sociodemographic characteristics of HIV-positive patients on isoniazid preventive therapy in Gondar, 2016

Variables	Categories	Frequency (n=154)	Percent
Sex	Male	80	51.9
	Female	74	48.1
Age	18–30	81	54.5
	31–40	51	33.1
	>40	19	12.3
Level of education	Illiterate	10	6.5
	Primary school	105	68.2
	Secondary school	28	18.2
	Diploma and above	11	7.1
Religion	Orthodox	139	90.1
	Protestant	1	0.6
	Muslim	14	9.1
Ethnicity	Amhara	144	93.5
	Oromo	2	1.2
	Tigre	7	4.5
	Gurage	1	0.6
Family size	<5	118	76.6
	6–10	33	21.4
	>10	3	1.9
Occupation	Self-employed	45	29.2
	Government	26	16.9
	employed
	Housewives	33	21.4
	Merchants	37	24.0
	Farmers	11	7.1
	Students	2	1.3
Monthly income	<250 ETB	71	46.1
	251–999 ETB	47	30.5
	>1,000 ETB	36	23.4
WHO HIV/AIDS stage	1 and 2	36	23.4
	3	116	75.3
	4	2	1.3

Note: 1 USD =21.85 Birr.

Abbreviations: ETB, Ethiopian Birr; USD, United States dollar; WHO, World Health Organization.

Table 2 Cross-tabulation of respondents’ adherence with their occupation, Gondar, 2016

Occupation	Adherence		Total	Percent
	Adherent (%)	Nonadherent (%)
Students	2 (1.30)	0 (0.0)	2	1.30
Merchants	33 (21.43)	4 (2.60)	37	24.03
Housewives	31 (20.13)	2 (1.30)	33	21.43
Farmers	11 (7.14)	0 (0.0)	11	7.14
Government employees	21 (13.64)	5 (3.25)	26	16.88
Servants	41 (26.62)	4 (2.60)	45	29.22
Total	139 (90.26)	15 (9.74)	154	100

Table 3 Factors associated with IPT adherence among HIV-positive patients in Gondar, 2016

Variables	Adherence		OR (95% CI)
	Yes	No	Crude	Adjusted
Sex
Male	73	7	0.79 (0.27–2.30)	1.39 (0.20–9.56)
Female	66	8	1	1
Age
18–30	75	9	1	1
31–40	46	5	2.16 (0.26–18.16)	1.16 (0.23–5.92)
.40	18	1	1.96 (0.21–17.92)	0.44 (0.34–6.50)
Occupation
Self-employed	52	4	1	1
Government employer	21	5	1.24 (0.28–5.35)	1.38 (0.18–10.23)
Housewives	31	2	0.66 (0.11–3.84)	0.38 (0.03–4.37)
Merchants	33	4	2.44 (0.59–10.05)	3.941 (0.29–52.95)
Students	2	0	0.000	0.000
Duration of IPT
1–2 months	39	6	1	1
≥3 months	100	9	2.48 (0.37–18.26)	0.09 (0.10–0.79)
Explanation about IPT regimen
Yes	105	13	1	1
No	34	2	0.47 (0.10–2.21)	0.26 (0.23–3.12)
INH may be dangerous to your health
Strongly disagree	33	3	1	1
Strongly agree	4	3	8.5 (1.64–44.03)	9.44 (0.62–128.48)
Do not know	102	9	1.09 (0.28–4.30)	2.45 (0.37–15.99)
Chance of getting sick from TB without treatment
High	107	17	1	1
Average/below average	19	0	1.26 (0.25–6.43)	8.79 (0.85–91.08)
Do not know	13	2	0.00	0.00
Side effects
Yes	45	3	0.24 (0.07–0.74)	0.64 (0.27–10.03)
No	100	6	1	1
ART status
Pre-ART	16	8	0.24 (0.07–0.73)	1.68 (0.27–10.03)
On ART	109	21	1	1
ART regimen
AZT+3TC+NVP	85	8	1	1
AZT+3TC+EFV	15	4	0.84 (0.16–4.33)	0.08 (0.003–2.17)
TDF+3TC+NVP	11	1	0.429 (0.03–5.12)	0.144 (0.015–1.42)
TDF+3TC+EFV	18	12	2.4 (0.38–14.97)	1.114 (0.09–13.21)
INH makes me tired
Yes	79	11	0.48 (0.14–1.58)	1.59 (0.27–9.42)
No	60	4	1	1

Abbreviations: AZT, zidovudine; ART, antiretroviral therapy; CI, confidence interval; EFV, efavirenz; OR, overall ratio; INH, isonizid; IPT, isoniazid preventive therapy; NVP, nevirapine; TB, tuberculosis; TC, lamivudine; TDF, tenofovir.

Figure 1 Reasons for nonadherence among HIV-positive patients, Gondar, 2016.

Abbreviation: INH, isonizid.