Acceptance of COVID-19 Vaccine and Determinant Factors Among Patients with Chronic Disease Visiting Dessie Comprehensive Specialized Hospital, Northeastern Ethiopia

Figures & data

Table 1 Socio-Demographic Characteristics of Patients with Chronic Disease Visiting in Dessie Comprehensive Specialized Hospital, Northeastern Ethiopia May 1 to 20, 2021

Variable	Category	Frequency(n) (%)
Sex	Male	185 (49.6)
	Female	231 (50.4)
Age (years)	18–29	133 (32.0)
	30–39	97 (23.3)
	40–49	67 (16.1)
	50–59	43 (10.3)
	>60	76 (18.3)
Religion	Orthodox	174 (41.8)
	Muslim	202 (48.6)
	Protestant	40 (9.6)
Marital status	Single	90 (21.6)
	Married	312 (75.0)
	Widowed	14 (3.4)
Highest educational level	Unable to read and write	78 (18.7)
	Informal education	119 (28.6)
	Primary (grade1-8)	57 (13.7)
	Secondary (grade 9–12	39 (9.4)
	College and above	123 (29.6)
Residence	Urban	226 (54.3)
	Rural	190 (45.7)
Occupation	Housewife	115 (27.6)
	Private worker	59 (14.2)
	Farmer	81 (19.5)
	Government employer	81 (19.5)
	Unemployed	80 (19.2)
Smoking status	Never smoked	336 (80.8)
	Former smoker	52 (12.5)
	Current smoker	28 (6.7)
Presence of health insurance	Yes	212 (60.0)
	No	204 (40.0)
Presence of high-risk groups in househlds	Yes	213 (51.2)
	No	203 (48.8)
History of vaccine	Yes	215 (51.7)
	No	201 (48.3)
Travel history	Yes	246 (59.1)
	No	170 (40.9)
Average monthly income ($)	≤ 37.5	102 (24.5)
	37.525–75	218 (52.4)
	≥75.025	96 (23.1)
Types of chronic illness	Hypertension	62 (14.9)
	Respiratory disease	111 (26.7)
	Diabetes mellitus	86 (20.7)
	HIV	89 (21.4)
	Heart disease	55 (13.2)
	Others*	13 (3.1)
Duration of attending follow up	Less than five years	76 (18.3)
	5–10 years	150 (36.0)
	>10 years	190 (45.7)
Do you know anyone diagnosed with COVID-19	Yes	199 (47.8)
	No	217 (52.2)

Note: *Cancer, renal, liver disease.

Table 2 Sources of Information Towards COVID-19 Vaccine Among Patients with Chronic Diseases Visiting in Dessie Comprehensive Specialized Hospital, Northeast Ethiopia May 1–20, 2021 (N=416)

Sources of Information on COVID-19 Vaccine	Frequency	Percentage
Health professionals	141	33.9
Friends	262	63.0
Nighbours	358	86.1
Famil members	330	79.3
Newsaers	84	20.2
Internet	115	27.6
Social media	189	45.4
Mass media (radio and television)	192	46.2

Table 3 Knowledge About COVID-19 Vaccine Among Patients with Chronic Disease Visiting in Dessie Comprehensive Specialized Hospital, Northeastern Ethiopia, May 1–20, 2021

Items	Yes	No	I Do Not Know
	n (%)	n (%)	n (%)
COVID-19 can be prevented by the vaccine.	336 (80.8)	55 (13.2)	25 (6.0)
AstraZeneca and Covishield are the two vaccines used in Ethiopia.	205 (49.3)	78 (18.7)	133 (32.0)
The vaccine is given two times within 28 days apart	190 (45.7)	81 (19.5)	145 (34.8)
The vaccine is provided for free in Ethiopia	310 (74.5)	74 (1.8)	32 (7.7)
The provision of the vaccine is based on voluntary not obligatory.	343 (82.5)	53 (12.7)	20 (4.8)
Healthcare professionals, chronic patients, and elders are the prioritized groups for vaccination	325 (78.1)	49 (11.8)	42 (10.1)
The vaccine of COVID-19 vaccine has started	211 (50.7)	124 (29.8)	81 (19.5)

Table 4 Attitude Towards the COVID-19 Vaccine Among Patients with Chronic Diseases visiting in Dessie Comprehensive Specialized Hospital, Northeastern Ethiopia, May 1 to 20, 2021

Attitude Related Questions	Agree	Neutral	Disagree
	N (%)	N (%)	N (%)
Does the COVID-19 vaccine is essential for you?	253 (60.8)	65 (15.6)	98 (23.6)
Do you think COVID-19 can be prevented by the vaccine?	286 (68.8)	88 (21.2)	42 (10.0)
The vaccine of covid-19 should be given to all	170 (40.9)	153(36.8)	93 (22.3)
COVID-19 vaccine is against your culture.	219 (52.6)	126 (30.3)	71 (17.1)
COVID-19 vaccine will save our time	215 (51.7)	164 (39.4)	37 (8.9)
COVID-19 vaccine will save money	234 (56.3)	119 (28.6)	63 (15.1)
Do you think you are susceptible to the infection of COVID-19 disease?	211 (50.7)	138 (33.2)	67 (16.1)
It is not possible to reduce the incidence of COVID-19 without vaccination	253 (60.8)	119 (28.6)	44 (10.6)

Table 5 Social and Political Factors Affecting COVID-19 Vaccine Acceptance Among Patients with Chronic Diseases Attending Dessie Comprehensive Specialized Hospital, Northeastern Ethiopia, May 1 to 20, 2021

Variables	Category	Frequency	Percentage
Self-reported perception risk of COVId-19	Low risk	319	76.7
	High risk	97	23.3
Trust in the government	Yes	345	82.9
	No	71	17.1
Trust on public health authorities	Yes	275	66.1
	No	141	33.9
Trust on vaccine manufacturer	Yes	265	63.7
	No	151	36.3

Table 6 Factors Associated with Willingness to Accept the COVID-19 Vaccine Among Patients with Chronic Diseases Visiting Dessie Comprehensive Specialized Hospital, Northeastern Ethiopia, May 1–20, 2021

Variable		Willingness		COR (95% CI)	AOR (95% CI)	P-value
		Yes	no
Sex	Male	118	67	1.393 (0.937–2.071	1.525 (0.889–2.587)	0.117
	Female	129	102	1	1
Marital status	Single	64	26	1	1
	Married	176	136	0.526 (0.265–2.256)	1.286 (0.296–5.586)	0.737
	Widowed	7	7	0.406 (0.130–1.273)	0.596 (0.126–2.818)	0.514
Religion	Orthodox	117	57	0.988 (0.475–2.058)	1.644 (0.625–4.326)	0.314
	Muslims	103	99	0.5.07 (0.4752.058)	1.644 (0.625–4.326)	<0.0001
	Protestant	27	13	1	1
Health insurance	Yes	136	76	1.499 (1.012–2.222)	1.812 (1.703–3059)	0.026
	No	111	93	1	1
Vaccination history	Yes	126	75	1.305 (0.881–1.933)	1.263 (0.750–2.126)	0.380
	No	121	94	1	1
Know diagnosed with covid-19	Yes	129	70	1.546 (1.042–2.295)	2.482 (1.427–4.317)	0.001
	No	118	99	1	1
Trust the gov’t of Ethiopia	Yes	213	132	1.756 (1.051–2.935)	1.322 (0.653–2.675)	0.438
	No	34	37	1	1
Risk on COVID-19	Low risk	184	136	1	1
	High risk	64	33	1.441 (0.896–2.138)	1.355 (0.722–2.543)	0.344
Knowledge	Poor	40	115	1	1
	Good	207	54	11.021 (6.901–17.600)	6.890 (3.900–12.170)	<0.0001
Attitude	Negative	24	94	1	1
	Positive	223	75	11.646 (6.930–19.569)	7.725 (4.024–14.830)	<0.0001