Questionnaire Survey on Vaccination Willingness and the Status of COVID-19 Vaccination Among Patients with Rheumatic Disease: A Single-Center Survey in China

Figures & data

Table 1 Demographic Details of the Study Participants

Variables	Total Participants (Number=417)	Percentage
Sex
Male	125	29.98
Female	292	70.02
Age (years)
18–29	39	9.35
30–39	77	18.47
40–49	123	29.50
50–59	122	29.26
60–65	39	9.35
65 and older	17	4.08
Marital status
Married	376	90.17
Unmarried	33	7.91
Divorced or widowed	8	1.92
Place of residence
Cities	184	44.12
Counties	96	23.02
Towns	32	7.67
Villages	104	24.94
No fixed place of residence	1	0.24
Occupation
Medical	19	4.56
Nonmedical	398	95.44
Occupations of family members, relatives, and friends
Medical	124	29.74
Nonmedical	293	70.26

Table 2 Analysis of the Impact of Demographic Details on the Perception of COVID-19 Infection Risk

Items	Variables	Number	Mean ± SD	F	p
Sex	Male	125	3.18±2.21	11.288	0.001
	Female	292	3.98±2.26
Age	18–29	39	3.21±2.17	0.985	0.427
	30–39	77	3.56±2.21
	40–49	123	4.02±2.28
	50–59	122	3.82±2.28
	60–65	39	3.64±2.39
	65 and older	17	3.47±2.48
Marital status	Married	376	3.77±2.28	0.852	0.427
	Unmarried	33	3.27±2.24
	Divorced or widowed	8	4.13±2.23
Place of residence	Cities	84	3.58±2.24	1.628	0.166
	Counties	96	3.89±2.28
	Towns	32	3.16±2.30
	Villages	104	4.06±2.30
	No fixed place of residence	1	6.00±null
Occupation	Medical	19	3.26±2.16	0.878	0.349
	Nonmedical	398	3.76±2.28
Occupations of family members, relatives, and friends	Medical	124	3.76±2.21	0.010	0.921
	Nonmedical	293	3.73±2.30

Table 3 Analysis of the Impact of Sex on the Perception of COVID-19 Infection Risk

Questions	Options	Sex: n (%)		Total	χ^2	p
		Male	Female
What do you think your risk of infection with COVID-19 is?	No risk at all	46(36.80)	81(27.74)	127(30.46)	13.641	0.018
	Negligible risk	22(17.60)	31(10.62)	53(12.71)
	Medium risk	10(8.00)	14(4.79)	24(5.76)
	Considerable risk	2(1.60)	7(2.40)	9(2.16)
	Extremely high risk	1(0.80)	4(1.37)	5(1.20)
	Unclear	44(35.20)	155(53.08)	199(47.72)
Total		125	292	417

Table 4 ANOVA Between Demographic Details and the Perception of the Impact of COVID-19 Infection on Rheumatic Disease

Items	Variables	Number Mean ± SD		F	p
Sex	Male	125)	4.33±2.06	3.419	0.065
	Female	292	4.71±1.89
Age	18–29	39	4.49±1.79	0.923	0.466
	30–39	77	4.78±1.74
	40–49	123	4.63±1.99
	50–59	122	4.60±1.99
	60–65	39	4.05±2.24
	65 and older	17	5.00±1.94
Marital status	Married	376	4.61±1.97	2.487	0.084
	Unmarried	33	4.18±1.88
	Divorced or widowed	8	5.88±0.35
Educational level	Junior high school and below	189	4.56±2.06	0.239	0.787
	High school or vocational school	115	4.70±1.95
	College and above	113	4.56±1.77
Place of residence	Cities	184	4.50±1.92	1.344	0.253
	Counties	96	4.57±2.00
	Towns	32	4.16±2.22
	Villages	104	4.91±1.84
	No fixed place of residence	1	6.00±null
Occupation	Medical	19	3.53±2.09	6.074	0.014
	Nonmedical	398	4.65±1.93
Occupations of family members, relative, and friends	Medical	124	4.48±1.87	0.682	0.409
	Nonmedical	293	4.65±1.99

Table 5 Chi-Square Analysis Between the Occupations (Medical versus Nonmedical) of the Participants and Their Perceptions of the Impact of COVID-19 Infection on Rheumatic Disease

Questions	Options	Occupation (%)		Total	χ^2	p
		Medical	Nonmedical
How much do you think your rheumatic disease will be affected if you are infected with COVID-19?	No impact at all	6(31.58)	58(14.57)	64(15.35)	11.557	0.041
	Negligible impact	1(5.26)	29(7.29)	30(7.19)
	Medium impact	2(10.53)	18(4.52)	20(4.80)
	Considerable impact	2(10.53)	27(6.78)	29(6.95)
	Extremely tremendous impact	3(15.79)	24(6.03)	27(6.47)
	Unclear	5(26.32)	242(60.80)	247(59.23)
Total		19	398	417

Table 6 Logistic Regression Analysis of Factors Influencing COVID-19 Vaccine Willingness

Variables	β	p	OR	VIF	95% CI
Sex	−0.201	0.000	−0.851	1.092	−1.260 ~ −0.441
Age	0.028	0.606	0.043	1.285	−0.121~0.207
Marital status	−0.058	0.251	−0.297	1.129	−0.803~0.209
Place of residence	−0.007	0.899	−0.011	1.329	−0.179~0.157
Occupation	0.173	0.001	1.609	1.110	0.702~2.516
Occupations of family members, relatives, and friends	−0.098	0.049	−0.416	1.108	−0.829 ~ −0.002
Disease assessment	0.016	0.732	0.087	1.037	−0.411~0.585
Perception of COVID-19 infection risk	−0.018	0.760	−0.016	1.632	−0.117~0.085
Perception of the impact of COVID-19 infection on rheumatic disease	−0.154	0.012	−0.154	1.683	−0.273 ~ −0.034
Perception of the impact of COVID-19 vaccination on rheumatic disease	0.084	0.088	0.068	1.071	−0.010~0.145
Vaccination with other vaccines in the last 5 years (other than the COVID-19 vaccine)	−0.045	0.360	−0.292	1.073	−0.917~0.332
Sample size	417
R^2	0.100
Adjusted R^2	0.074
F value	F (12,404)=3.754, p=0.000

Note: Dependent variable: willingness to be vaccinated against COVID-19. D-W value: 1.831.

Table 7 ANOVA of the Degree of Willingness and Factors Influencing the Degree of Willingness to Be Vaccinated Against COVID-19

Items	Variables	Number	Mean ± SD	F	p
Sex	Male	125	6.35±1.30	15.503	0.000
	Female	292	5.55±2.12
Occupation	Medical	19	4.63±2.65	7.164	0.008
	Nonmedical	398	5.84±1.89
Occupations of family members, relatives, and friends	Medical	124	5.94±1.91	1.003	0.317
	No-medical	293	5.73±1.96
Perception of the impact of COVID-19 infection on rheumatic disease	No impact at all	64	6.58±1.48	5.161	0.000
	Negligible impact	30	6.33±1.15
	Medium impact	20	5.10±2.45
	Considerable impact	29	5.55±1.72
	Tremendous impact	27	4.70±1.81
	Unclear	247	5.72±2.04