Clinical outcomes of transfusion-associated iron overload in patients with refractory chronic anemia

Figures & data

Table 1 Hematologic characteristics of 13 patients with transfusion-associated iron overload

Patient	Sex	Age (years)	Diagnosis	Transfusion units	SF (ng/mL)
1	F	55	Refractory anemia	280	3,564
2	M	25	Chronic aplastic anemia	252	4,586
3	M	60	Chronic aplastic anemia	236	4,339
4	M	73	Myeloproliferative disease	320	4,085
5	M	26	Severe aplastic anemia	180	3,596
6	F	56	Chronic aplastic anemia	246	3,687
7	F	47	Chronic aplastic anemia	144	3,586
8	F	52	5q-syndrome	288	4,258
9	F	25	Severe aplastic anemia	384	1,857
10	M	68	Chronic aplastic anemia	54	1,830
11	M	32	Severe aplastic anemia	92	1,985
12	M	82	Refractory anemia with ringed sideroblasts	78	2,550
13	M	43	Thalassemia	40	5,740

Abbreviations: SF, serum ferritin; M, male; F, female.

Figure 1 Correlation between Hounsfield units (HU) and serum ferritin levels in patients with transfusion-associated iron overload.

Abbreviations: CT, computed tomography; SF, serum ferritin.

Table 2 Hepatic evaluation in 13 patients with transfusion-associated iron overload

Variable	Patients with abnormal results (n)
Alanine aminotransferase	10
Glutamic oxaloacetic transaminase	8
Alkaline phosphatase	5
Gamma-glutamyl transferase	5
Bilirubin	4
Albumin	6